METHOD OF MANUFACTURING CELL SPHEROID USING THREE-DIMENSIONAL PRINTING METHOD
First Claim
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1. A method of manufacturing a cell spheroid using a three-dimensional printing method, comprisingpreparing a bioink comprising cells, decellularized extracellular matrix and alginate;
- andmanufacturing a cell spheroid by printing the bioink using the three-dimensional printing in a micro-extrusion manner.
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Abstract
The present invention relates to a method of manufacturing a cell spheroid using three-dimensional bio-printing technology, and the cell spheroid may be used for preventing or treating vascular and endocrine diseases by including mesenchymal stem cells, induced pluripotent stem cells-derived cells, or the like as an active ingredient, or may be used as an in vitro drug testing model.
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20 Claims
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1. A method of manufacturing a cell spheroid using a three-dimensional printing method, comprising
preparing a bioink comprising cells, decellularized extracellular matrix and alginate; - and
manufacturing a cell spheroid by printing the bioink using the three-dimensional printing in a micro-extrusion manner. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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- 19. A composition for manufacturing a cell spheroid using a three-dimensional printing method, comprising cells, decellularized extracellular matrix and alginate as a gelated polymer.
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