APTAMERS FOR MEASURING LIPOPROTEIN LEVELS
First Claim
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1. An aptamer with high affinity to LDL particles and high selectivity for LDL particles over HDL particles.
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Abstract
Provided herein are aptamers for binding lipoproteins, systems for binding lipoproteins, and methods of detecting lipoproteins in a sample. The aptamers are useful for detecting the levels of lipoproteins in a biological sample and selectively detecting LDL particles in the presence of HDL particles. The aptamers can also be used as therapeutic agents against various diseases.
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Citations
53 Claims
- 1. An aptamer with high affinity to LDL particles and high selectivity for LDL particles over HDL particles.
- 19. A system comprising a plurality of aptamers, wherein the aptamers have a high affinity to LDL particles and high selectivity for LDL particles over HDL particles.
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