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SRM/MRM Assays For Notch Pathway Proteins

  • US 20200132696A1
  • Filed: 10/29/2019
  • Published: 04/30/2020
  • Est. Priority Date: 10/30/2018
  • Status: Abandoned Application
First Claim
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1. A method for measuring the level of protein in a biological sample of formalin fixed tissue, the method comprisingdetecting and/or quantifying by mass spectrometry an amount of one or more modified or unmodified fragment peptides derived from the protein in a protein digest prepared from said biological sample;

  • and calculating the level of said protein in said sample;

    wherein said protein is selected from the group consisting of DLL1, DLL3, JAG1, JAG2, Notch1, Notch 2, Notch 3, Notch 4, and DLL4 protein.

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