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Method and System of Identifying and Quantifying A Protein

  • US 20200132697A1
  • Filed: 10/30/2019
  • Published: 04/30/2020
  • Est. Priority Date: 10/31/2018
  • Status: Active Grant
First Claim
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1. A method for quantifying an impurity in a sample, said method comprising:

  • contacting said sample to a chromatographic system having a mixed-mode size exclusion chromatography resin with an additional functionality;

    washing said mixed-mode size exclusion chromatography resin using a mobile phase to provide an eluent including the impurity; and

    quantifying an amount of the impurity in said eluent using a mass spectrometer.

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