Medicinal tablets

• US 3,113,076 A
• Filed: 07/03/1956
• Issued: 12/03/1963
• Est. Priority Date: 07/03/1956
• Status: Expired due to Term

• Current Assignee: Henry R. Jacobs
• Original Assignee: Henry R. Jacobs
• Inventors: Jacobs, Henry R.
• Application Number:
  US03/595,658
• Time in Patent Office: 2,709 Days
• US Class Current: 424/467
• CPC Class Codes: A61J 3/10 into the form of compressed tablets tablet presses B30B11/00
• CPC Class Codes: A61K 9/2072 characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms A61K9/0004, A61K9/0056, A61K9/0065 take precedence

Claims

1. A MEDICAMENT PRODUCT IN SOLID TABLET FORM, DESIGNED TO BE TAKEN INTERNALLY AND CONTROLLABLY TO RELEASE ACITVE MEDICAMENT THEREFROM INTO THE BODY OF A LIVING ANIMAL OVER AN APPRECIABLE TIME INTERVAL, COMPRISING A TABLET CONTAINING A SUBSTANTIALLY UNIFORM MIXTURE INCLUDING A PHARMACEUTICALLY ACCEPTABLE VEHICLE AND AN ACTIVE MEDICAMENT, SAID TABLET HAVING AT LEAST ONE APERTURE THEREIN HAVING A PREDETERMINED TOTAL INNER SURFACE AREA SO RELATED TO THE TOTAL OUTER SURFACE AREA OF SAID TABLET THAT, DURING DISINTEGRATION OF SAID MEDICAMENT PRODUCT IN THE BODY OF A LIVING ANIMAL, THE TOTAL AREA OF SAID MEDICAMENT PRODUCT SUBJECT TO DISINTEGRATION AND RELEASE OF ACTIVE MEDICAMENT REMAINS RELATIVELY CONSTANT, WHEREBY SAID ACITIVE MEDICAMENT IS RELEASED AT A MATERIALLY MORE CONSTANT RATE OVER SAID APPRECIALBE TIME INTERVAL THAN WOULD BE ACHIEVED BY A CONVENTIONAL SOLID TABLET DEVOID OF SAID APERTURE.