CATHETER

• US 3,566,874 A
• Filed: 08/13/1968
• Issued: 03/02/1971
• Est. Priority Date: 08/13/1968
• Status: Expired due to Term

• Current Assignee: Francis E. Gould, Thomas H. Shepherd
• Original Assignee: Francis E. Gould, Thomas H. Shepherd
• Inventors: Shepherd, Thomas H., Gould, Francis E.
• Application Number:
  US04/752,221
• Time in Patent Office: 931 Days
• US Class Current: 604/265
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/406 Antibiotics
• CPC Class Codes: A61L 29/085 Macromolecular materials
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61M 2025/0056 provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
• CPC Class Codes: A61M 2025/1031 Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
• CPC Class Codes: A61M 25/0009 Making of catheters or other medical or surgical tubes
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61M 25/0045 multi-layered, e.g. coated coating materials A61L29/08
• CPC Class Codes: A61M 25/1027 Making of balloon catheters
• CPC Class Codes: C08L 33/14 of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
• CPC Class Codes: F02M 15/027 Air or air-fuel mixture preheating

Abstract

Catheters are provided with coating of a hydrophilic acrylate or methacrylate polymer. The coating reduces the irritation and infection normally accompanying the use of catheters. Infection can be reduced still further by absorbing an antibiotic in the coating.

Claims

1. A flexible ureteral, urethral or cannular infection preventing tubular catheter made of natural or synthetic rubber or other flexible polymer having an adherent, solid external coating of a polymeric compound of the group consisting of hydrophilic acrylate and methacrylate polymers, said coating by itself being effective in preventing infections.

2. A catheter according to claim 1 wherein the infection preventing polymer is further impregnated with a member of the group consisting of antibiotics and germIcides.

3. A catheter according to claim 1 wherein the polymeric compound is selected from the group consisting of polymers of hydroxy lower alkyl acrylates, hydroxy lower alkyl methacrylates, hydroxy lower alkoxy loweralkyl acrylates, and hydroxy lower alkoxy lower alkyl methacrylates.

4. A catheter according to claim 3 wherein the hydrophilic polymer is a copolymer of said acrylate or methacrylate with a minor amount up to 20 percent of a cross-linking monomer.

5. A ureteral catheter according to claim 4.

6. A cannulae catheter according to claim 4.

7. A ureteral catheter according to claim 4 wherein the polymeric compound is 2-hydroxyethyl methacrylate and the cross-linking agent is a polyethylenically unsaturated monomer present in an amount of 0.1 to 2.5 percent.

8. A ureteral catheter according to claim 7 made of rubber.

9. A ureteral catheter according to claim 8 wherein the polymer is impregnated with an antibiotic.

10. A process of reducing the danger of infection normally present when using a catheter in a human comprising inserting into an appropriate organ of the human body a catheter according to claim 1.

11. A catheter according to claim 1 wherein the coating is dry.

12. A catheter according to claim 4 wherein there is uncross-linked hydrophilic polymer coating of said acrylate or methacrylate over said copolymer coating, said copolymer serving to adhere the uncross-linked polymer to the catheter.