8-SUBSTITUTED-1-OXA-3,8-DIAZASPIRO(4,5)DECAN-2-ONES

• US 3,594,386 A
• Filed: 12/18/1968
• Issued: 07/20/1971
• Est. Priority Date: 12/29/1967
• Status: Expired due to Term

• Current Assignee: Douarec Jean-Claude Le, Gilbert Regnier, Roger Canevari
• Original Assignee: Douarec Jean-Claude Le, Gilbert Regnier, Roger Canevari
• Inventors: Regnier, Gilbert, Canevari, Roger, DOUAREC JEAN-CLAUDE LE
• Application Number:
  US04/784,871
• Time in Patent Office: 944 Days
• US Class Current: 546/19
• CPC Class Codes: C07D 498/10 Spiro-condensed systems

Abstract

1-OXA-2-OXO-3,8-DIAZO SPIRO (4,5) DECANES SUBSTITUTED IN 8-POSITION BY

(1) AR-X-(CH2)N

WHEREIN X IS -CO-, -CHOH-, -CH(OCH2)-,

-C(-C6H5)(-OH)-

N IS 1, 2 OR 3, AND AR IS PHENYL OR MONO- OR DI-HALO-PHENYL, OR

(2) AR-(CH2)2-

WHEREIN AR IS 2-PYRIDYL OR 4-PYRIDYL OR CERTAIN SUBSTITUTED PHENYL. THESE COMPOUNDS POSSESS ANALGESIC, ANTIINFLAMMATORY, CENTRAL NERVOUS SYSTEM DEPRESSANT AND BRONCHODILATOR PROPERTIES.

Claims