DEVICES FOR TESTING BIOLOGICAL LIQUIDS
First Claim
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2. A testing device as defined in claim 1 wherein said one surface of the membrane has substantially no surface roughness larger than the size of red blood corpuscles.
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Abstract
Testing devices for biological liquids comprise liquid permeable membranes of uniform chemical composition having a solid diagnostic reagent composition incorporated in at least a portion thereof and having at least one surface portion impenetrable by particles of the order of size of red blood corpuscles. The membranes may be of substantially uniform porosity throughout or they may have a thin skin portion of low effective porosity and a thicker body portion having pores of substantially large effective diameters.
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Citations
7 Claims
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2. A testing device as defined in claim 1 wherein said one surface of the membrane has substantially no surface roughness larger than the size of red blood corpuscles.
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3. A testing device as defined in claim 1 wherein said one surface of the membrane is impenetrable by particles of the order of size of hemoglobin molecules.
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4. A testing device as defined in claim 1 wherein said one surface of the membrane is penetrable by particles not exceeding about 20,000 in molecular weight and impenetrable by particles exceeding about 50,000 in molecular weight.
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5. A testing device as defined in claim 1 wherein a portion of the membrane other than said one surface is penetrable by particles substantially larger than particles capable of penetrating said one surface.
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6. A testing device as defined in claim 1 wherein at least the portion of the membrane other than said one surface includes therein a solid diagnostic reagent composition.
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7. A testing device as defined in claim 1 wherein the diagnostic reagent composition is responsive by a color change to the presence of glucose in biological liquids in contact with the membrane.
Specification