COMPOSITION CONTAINING GEL
First Claim
2. The method of claim 1 wherein said liquid medium is glycerin.
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Abstract
A new plastic composition which is slow dissolving in aqueous media and can be used to slowly release medication or other additive ingredients in an aqueous environment, which plastic composition is prepared by cross-linking a hydrophilic colloid such as carboxymethyl cellulose gum or alginate gum with a crosslinking agent, usually a polyol such as propylene glycol, in a relatively nonreactive water soluble carrier such as glycerol. The total composition, including the carrier, sets up into a plastic gel, the consistency of which can be varied by varying proportions of ingredients. The reaction can be speeded or driven to a more completely cross-linked state by using a catalysts such as aluminum or calcium salts. Complexing agents can be included for complexing the catalysts and releasing it slowly throughout the reaction to slow the reaction down where desired. Generally, the reaction proceeds faster in a close to neutral or basic medium at pH'"'"''"'"'s ranging up to 10 or 11 and slower in an acid medium at pH of 5 and below so the rate of reaction can be controlled by adjusting the pH. Usually the composition will contain medication or cosmetic additives or ingredients and it can be molded by extrusion or the like into any predetermined form, e.g., in the form of a ring. In a preferred form, the composition has excellent pressure sensitive adhesive properties and these properties are very pronounced where the hydrophilic colloid used is carboxymethyl cellulose.
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Citations
14 Claims
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2. The method of claim 1 wherein said liquid medium is glycerin.
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3. The method of claim 1 wherein the reacting mass includes from 0.2 to 2 parts by weight of a catalyst selected from the group consisting of calcium carbonate, calcium chloride, sodium benzoate, benzoic acid and aluminum hydroxide.
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4. The method of claim 3 wherein said catalyst is aluminum hydroxide.
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5. The method of claim 3 wherein the catalyst is selected from the group consisting of calcium carbonate and calcium chloride.
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6. The method of claim 3 wherein the catalyst is selected from the group consisting of benzoic acid and sodium benzoate.
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7. The method of claim 1 wherein the pH of the reaction mixture is above about 5.
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8. The method of claim 7 wherein the pH of the reaction mixture is below about 11.
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9. The method of claim 1 including the step of including starch in the reacting mass in an amount in the range of 10 to 50 weight percent based on total carrier and cross-linked gum.
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10. The method of claim 9 including the step of precoating the starch with wetting agent before its inclusion in the reaction mass.
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11. The method of claim 1 including the step of mixing medication with the colloid and polyol prior to gelling of the reaction mass.
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12. The method of claim 1 including the step of molding the reaction mass to a form.
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13. The method of claim 12 wherein said molding step comprises extruding the reaction mass as it is gelling to plastic consistency.
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14. The method of claim 1 including the step of adding the gel to a lotion base water emulsion until the emulsion is brought up to creamy consistency.
Specification