4 HYDROXY-ALPHA'AMINOMETHYL-M-XYLENE-ALPHA' ALPHA**3-DIOLS

• US 3,644,353 A
• Filed: 09/20/1967
• Issued: 02/22/1972
• Est. Priority Date: 09/23/1966
• Status: Expired due to Term

• Current Assignee: Lunts Lawrence H C, Paul Toon
• Original Assignee: Lunts Lawrence H C, Paul Toon
• Inventors: LUNTS LAWRENCE H C, Toon, Paul
• Application Number:
  US04/669,263
• Time in Patent Office: 1,616 Days
• US Class Current: 544/162
• CPC Class Codes: C07C 229/38 having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
• CPC Class Codes: C07C 243/38 with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
• CPC Class Codes: C07D 295/13 to an acyclic saturated chain

Abstract

NOVEL 1-PHENYL-2-AMINO ETHANOL DERIVATIVES OF THE FORMULA:

1-(HO-),2-X,(R2-N(-R3)-CH(-R1)-CH(-OH)-)BENZENE

ARE DISCLOSED. SOME HAVE STIMULANT ACTION AND SOME HAVE BLOCKING ACTION ON B-ADRENERGIC RECEPTORS. A1-TERT.-BUTYLAMINOMETHYL-4-HYDROXY-M-XYLENE A1,A3-DIOL HAS A PARTICULARLY MARKED STIMULANT ACTION. PHARMACEUTICAL COMPOSITIONS ARE ALSO DISCLOSED OF WHICH AEROSOLS ARE PARTICULARLY EFFECTIVE.

Claims