REAGENT FOR DETERMINING BLOOD SUGAR
First Claim
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2. A reagent composition as claimed in claim 1 in which water is contained in an Amount of up to 5 percent by volume.
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Abstract
A color-producing reagent for determining blood sugar comprising o-toluidine, thiourea, an ethylene glycol mono-lower alkyl ether, phthalic acid, and dimethyl formamide as a solubilizing agent, is outstandingly sensitive even to very low blood sugar contents, as in hypoglycaemia, and exhibits prolonged color stability.
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Citations
6 Claims
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2. A reagent composition as claimed in claim 1 in which water is contained in an Amount of up to 5 percent by volume.
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3. Method for the determination of blood sugar which comprises mixing a blood sample with a reagent composition as claimed in claim 1 and measuring the resulting mixture photometrically as an indication of the blood sugar content.
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4. A reagent composition as claimed in claim 1 which comprises 0.05 - 2.5 percent by weight thiourea, 5 - 33 percent by weight phthalic acid, 25 - 65 percent by weight dimethyl formamide, 10 -50 percent by weight ethylene glycol mono-lower alkyl ether and 2.5 - 15 percent by weight o-toluidine, based on total weight of composition.
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5. A reagent composition as claimed in claim 4 which comprises 0.075 - 0.15 percent by weight thiourea, 20 - 25 percent by weight phthalic acid, 35 - 55 percent by weight dimethyl-formamide, 20 - 40 percent by weight ethylene glycol mono-lower alkyl ether and 7.5 - 10 percent by weight o-toluidine, based on total weight of composition.
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6. A reagent composition as claimed in claim 4 wherein the total volume of dimethyl formamide and of alkylene glycol mono-lower alkyl ether does not exceed 150 parts by volume. 7 Method for the determination of blood sugar which comprises mixing a blood sample with a reagent composition as claimed in claim 4 and measuring the resulting mixture photometrically as an indication of the blood sugar content.
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