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PARABIOTIC DIALYSIS APPARATUS

  • US 3,699,960 A
  • Filed: 01/04/1971
  • Issued: 10/24/1972
  • Est. Priority Date: 01/04/1971
  • Status: Expired due to Term
First Claim
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1. Apparatus for blood to blood exchange of substances between a first organism and a second organism, comprising in combination:

  • a. a first closed surface forming a first chamber designed to hold blood b. first conduit means fluidically communicating with the first chamber and arranged to attach to cannulation means associated with the first organism for supplying blood from the first organism to the first chamber;

    c. second conduit means fluidically communicating with the first chamber and arranged to attach to cannulation means associated with the first organism for returning blood from the first chamber to the first organism;

    d. a second closed surface forming a second chamber designed to hold blood;

    e. third conduit means fluidically communicating with the second chamber and arranged to attach to cannulation means associated with the second organism for supplying blood from the second organism to the second chamber;

    f. fourth conduit means fluidically communicating with the second chamber and arranged to attach to cannulation means associated with the second organism for returning blood from the second chamber to the second organism;

    g. a third chamber designed to hold physiological fluid, the third chamber comprising;

    aa. a first portion including a third closed surface designed to hold a physiological fluid; and

    bb. a second portion including a fourth closed surface designed to hold a physiological fluid; and

    h. first membrane means, forming at least a portion of the first surface, having a first face arranged to contact blood within the first chamber and having a second face arranged to contact physiological fluid within the first portion of the third chamber to form an interface between the first chamber and the third chamber;

    i. second membrane means, forming at least a portion of the second surface, having a first face arranged to contact blood within the second chamber and having a second face arranged to contact physiological flUid within the second portion of the third chamber to form an interface between the second chamber and the third chamber;

    j. fifth conduit means for fluidically interconnecting the portions of the third chamber to allow any physiological fluid within the third chamber to recycle, including;

    aa. a first portion fluidically communicating with the first portion of the third chamber for supplying fluid from the first portion and fluidically communicating with the second portion of the third chamber for returning fluid to the second portion;

    bb. a second portion fluidically communicating with the second portion of the third chamber for supplying fluid from the second portion and fluidically communicating with the first portion of the third chamber for returning fluid to the first portion;

    k. variable orifice means interconnected within one of the first and second portions of the fifth conduit means for allowing ultrafiltration between the first organism and the second organism;

    l. pump means connected to the other of the first and second portions of the fifth fluid conduit means, the pump means being designed to continually recycle the physiological fluid within the third chamber; and

    m. detector means positioned in relation to the third chamber so as to continually monitor the physiological fluid in the third chamber and provide an alarm indicating a membrane leak.

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