TEST STRIPS

• US 3,802,842 A
• Filed: 03/02/1972
• Issued: 04/09/1974
• Est. Priority Date: 04/16/1971
• Status: Expired due to Term

• Current Assignee: Hans-Georg Rey, Hans Lange, Peter Rieckmann, Walter Rittersdorf
• Original Assignee: Hans-Georg Rey, Hans Lange, Peter Rieckmann, Walter Rittersdorf
• Inventors: Lange, Hans, Rittersdorf, Walter, Rey, Hans-Georg, Rieckmann, Peter
• Primary Examiner(s): Reese, Robert M.
• Application Number:
  US05/232,315
• Time in Patent Office: 768 Days
• Field of Search: 23/253TP 116/114AM 195/13.5R
• US Class Current: 436/169
• CPC Class Codes: C12Q 1/28 involving peroxidase
• CPC Class Codes: C12Q 1/54 involving glucose or galactose
• CPC Class Codes: G01N 33/525 Multi-layer analytical elements
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10T 436/144444 Glucose
• CPC Class Codes: Y10T 436/146666 Bile pigment
• CPC Class Codes: Y10T 436/173076 Nitrite or nitrate

Abstract

Test strips for the detection of components in liquids, especially in body fluids, comprising a holder and at least one indicator layer containing detection reagents wherein one surface of the layer is attached to the holder and the other surface is covered with a fine meshwork.

Claims

2. Test strip as claimed in claim 1 wherein the surface of said indicator layer not lying on said holding means is covered with said fine meshwork covering and wherein the edges of the indicator layer are uncovered.

3. Test strip as claimed in claim 1 wherein the surface of said indicator layer not lying on said holding means is covered with said fine meshwork covering and wherein the longitudinal edges of the indicator layer are uncovered.

4. Test strip as claimed in claim 1 wherein said open surface is 40 to 60 percent of the total surface area.

5. Test strip as claimed in claim 1 wherein the meshwork is a nonwoven or a woven fabric.

6. Test strip as claimed in claim 1 wherein the indicator layer consists of an absorbent paper or fleece.

7. Test strip as claimed in claim 1 wherein said holding means is a synthetic resin strip.

8. Test strip as claimed in claim 1 wherein said holding means is a strip of an absorbent material impregnated or coated with a water-repellant material.

9. Test strip as claimed in claim 1, wherein the covering consists of a synthetic resin fabric with a filament thickness of 5 to 200 microns.

10. Test strip, as claimed in claim 9, wherein the covering consists of synthetic resin fabric with a filament thickness of 20 to 100 microns.

11. Test strip as claimed in claim 1 wherein at least two indicator layers lie on said holding means.

12. Test strip as claimed in claim 11 wherein the holding means is a flat strip and at least two indicator layers lie on the same surface of the flat strip holding means.

13. Test strip as claimed in claim 11 wherein the holding means is a flat strip and at least two indicator layers lie on the opposite surfaces of the flat strip holding means.

14. Test strip as claimed in claim 11 wherein said covering extends over all of said indicator layers and projects beyond the two end indicator layers, and is adhered to said holding means by adhesive strips disposed transversely between aDjacent indicator layers and beyond the two end indicator layers.

15. Test strip as claimed in claim 1 wherein said covering projects beyond said indicator layer and wherein peripheral zones of said covering projecting beyond the indicator layer are adhered to said holding means.

16. Test strip as claimed in claim 15 wherein said holding means is elongated and said covering projects longitudinally beyond said indicator layer.

17. Test strip as claimed in claim 16, wherein projecting zones of said indicator layer are adhered to the holding means by means of an adhesive layer disposed between said projecting zones and the holding means.

18. Test strip as claimed in claim 15 wherein an adhesive layer is provided between said holding means and said indicator layer and said adhesive layer extends beyond said surface to adhere said peripheral zones to the holding means.

19. Test strip as claimed in claim 18 wherein an additional absorbent layer is disposed between said adhesive layer and said indicator layer.

20. Method of detecting components in liquids, which method comprises contacting the liquid to be analyzed with a test strip comprising holding means and at least one indicator layer containing detection reagents, wherein one surface of the indicator layer lies on a portion of said holding means and the remainder of said indicator layer is substantially covered with a covering consisting of a fine meshwork wherein the open surface area of the holes is 30 to 80 percent of the total surface area of said meshwork.

21. Method as claimed in claim 20 wherein said liquids are body fluids.

22. Method as claimed in claim 20 wherein the surface of said indicator layer not lying on said holding means is covered with said fine meshwork covering and wherein the edges of the indicator layer are uncovered.