PROGRAMMABLE PHYSIOLOGICAL INFUSION

• US 3,809,871 A
• Filed: 12/01/1972
• Issued: 05/07/1974
• Est. Priority Date: 12/01/1972
• Status: Expired due to Term

• Current Assignee: Donald R. Young, Richard R. Adachi, Wayne H. Howard
• Original Assignee: Donald R. Young, Richard R. Adachi, Wayne H. Howard
• Inventors: Howard, Wayne H., Young, Donald R., Adachi, Richard R.
• Primary Examiner(s): Morrison, Malcolm A.
• Assistant Examiner(s): Smith, Jerry
• Application Number:
  US05/311,175
• Time in Patent Office: 522 Days
• Field of Search: 235/151.3,151.34 128/213,214E,214F
• US Class Current: 604/500
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

A programmable physiological infusion device and method are provided wherein a program source, such as a paper tape, is used to actuate an infusion pump in accordance with a desired program. The system is particularly applicable for dispensing calcium in a variety of waveforms. The invention described herein was made by employees of the United States Government and may be manufactured and used by or for the Government for Governmental purposes without the payment of any royalties thereon or therefor.

Claims

1. A method for studying body response to dynamic pulsatile chemical inputs which includes infusing a substance into a test animal over a period of time for raising and lowering the concentration of said substance according to a sustained and predetermined wave form, comprising the steps of recording a desired program on an information carrying medium, wherein said program includes a pulse-modulated wave form coded on said medium, sensing the pulses on said medium, feeding said sensed pulses to a solenoid piston infusion pump whereby said solenoid activated pump infuses predetermined amounts of said substance into said animal, said amounts corresponding to and being dependent upon the length and shape of said coded pulse-modulated wave form.

2. The method of claim 1 wherein said wave form is a sinusoidal wave and said test substance is calcium.

3. An apparatus for infusing a substance into an animal for raising and lowering the concentration of said substance at a predetermined rate and in a sustained and predetermined wave form comprising in combination:

a. a record of a desired infusion program, said program including a pulse-modulated wave form coded on an information carrying medium, b. means for reading said pulse-modulated wave form record and for converting said record into a series of pulses, c. means for converting said pulses into a series of uniform increments of a test substance, and d. means for injecting said increments of a test substance into an experimental animal.

4. The apparatus of claim 3 wherein said program is in the form of a paper tape having a series of dashes thereon wherein the distance between said dashes represents the time between desired infusion increments.

5. The apparatus of claim 4 wherein a photoelectric reader is employed to read said tape and a solenoid-type piston pump is employed to translate said dashes into increments of test substance.