ANESTHETIC-VASOCONSTRICTOR-ANTIHISTAMINE COMPOSITION FOR THE TREATMENT OF HYPERTROPHIED ORAL TISSUE
First Claim
2. A composition according to claim 1 wherein said antihistaminic compound is selected from the group consisting of antazoline hydrochloride, diphenhydramine hydrochloride thonzylamine hydrochloride, chlorphenamine maleate, pyrilamine maleate, pheniramine maleate and mixtures thereof.
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Abstract
A composition for the treatment of hypertrophied and hyperplastic oral tissue and the pain phenomena associated with this condition. The composition contains as essential ingredients thereof one or more alkaloids, such as the sympathomimetic amines, which are vasoconstrictors and effect vasoconstriction of the oral tissue, an antihistaminic agent which interfers with the access of histamine to the endothelial cells of the capillary membrane, and a topical anesthetic to relieve pain.
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Citations
9 Claims
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2. A composition according to claim 1 wherein said antihistaminic compound is selected from the group consisting of antazoline hydrochloride, diphenhydramine hydrochloride thonzylamine hydrochloride, chlorphenamine maleate, pyrilamine maleate, pheniramine maleate and mixtures thereof.
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3. A composition according to claim 1 wherein said anesthetic compound is selected from the group consisting of benzocaine hydrochloride, tetracaine hydrochloride and mixtures thereof.
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4. A treatment for tissue which is hypertrophied or hyperplastic comprising applying to the area to be treated the composition of claim 1.
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5. A toothpaste composition according to claim 1 comprising said alkaloid, anesthetic and said antihistaminic compounds, from about 0.001 to 0.5 percent of a preservative, from about 0.002 to 2.0 percent of a suspending agent and from about 1 to 21 percent of a moisture retainer, the remainder of said composition being water and said percentages being based on the weight of the total composition.
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6. A toothpaste composition according to claim 5 wherein said suspending agent is selected from the group consisting of sodium carboxymethylcellulose, methylcellulose, bentonite, acacia, sterculia gum and tragacanth, and wherein said moisture retainer is selected from the group consisting of glycerin, propylene glycol, sorbital, polyethylene glycol, diethylene glycol monoethyl ether, polysorbate, monolourate and polyoxyethylene sorbitan.
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7. A composition according to claim 1 further including from about 0.001 to 0.5 weight percent of a preservative selected from the group consisting of methylparaben, propylparaben, sodium bisulfite, sodium benzoate, sodium thiosulfate, chlorobutanol, themersoal and phenylmercuric acetate.
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8. A mouthwash composition according to claim 7 comprising an aqueous solution of said alkaloid, antihistaminic compound, anesthetic compound and preservative.
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9. A water soluble tablet composition according to claim 7 comprising a suspension of said alkaloid, antishistaminic compound, anesthetic compound and preservative in a suspending agent selected from the group consisting of sodium carboxymethylcellulose, methylcellulose, bentonite acacia, sterculia gum and tragaconth.
Specification