APPARATUS AND TECHNIQUE FOR PRESERVATION OF ISOLATED ORGANS THROUGH PERFUSION
First Claim
1. APPARATUS FOR PRESERVATION OF ISOLATED VIABLE ORGANS BY HYPOTHERMIC PERFUSION, COMPRISING AN ORGAN HOLDING CHAMBER, PUMPING MEANS FOR CIRCULATING OF A PERFUSATE HAVING A FIRST CONDUIT FOR ADMINISTERING PERFUSATE TO AN ARTERY OF AN ORGAN CONTAINED IN THE CHAMBER AND A SECOND CONDUIT IN COMMUNICATION WITH SAID FIRST CONDUIT AND WITH THE INTERIOR OF SAID CHAMBER FOR SUPPLYING PERFUSATE OVER THE OUTER SURFACE OF SAID ORGAN, VALVE MEANS FOR REGULATING THE PRESSURE OF SAID PERFUSATE BEING ADMINISTERED TO SAID ORGAN, HEAT EXCHANGER MEANS FOR COOLING THE PERFUSATE, A GAS-LIQUID FILM CONTACT OXYGENATOR CONTAINED IN SAID CHAMBER, SAID OXYGENATOR COMPRISING AT LEAST ONE INCLINED FLAT HYDROPHILIC SURFACE POSITIONED TO RECEIVE EFFLUENT FROM SAID ORGAN AND PERFUSATE SUPPLIED BY SAID SECOND CONDUIT, AND MEANS FOR SUPPLYING OXYGEN CONTAINING GAS TO THE INTERIOR OF SAID CHAMBER FOR CONTACT WITH PERFUSATE ON SAID HYDROPHILIC SURFACE.
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Abstract
1. APPARATUS FOR PRESERVATION OF ISOLATED VIABLE ORGANS BY HYPOTHERMIC PERFUSION, COMPRISING AN ORGAN HOLDING CHAMBER, PUMPING MEANS FOR CIRCULATING OF A PERFUSATE HAVING A FIRST CONDUIT FOR ADMINISTERING PERFUSATE TO AN ARTERY OF AN ORGAN CONTAINED IN THE CHAMBER AND A SECOND CONDUIT IN COMMUNICATION WITH SAID FIRST CONDUIT AND WITH THE INTERIOR OF SAID CHAMBER FOR SUPPLYING PERFUSATE OVER THE OUTER SURFACE OF SAID ORGAN, VALVE MEANS FOR REGULATING THE PRESSURE OF SAID PERFUSATE BEING ADMINISTERED TO SAID ORGAN, HEAT EXCHANGER MEANS FOR COOLING THE PERFUSATE, A GAS-LIQUID FILM CONTACT OXYGENATOR CONTAINED IN SAID CHAMBER, SAID OXYGENATOR COMPRISING AT LEAST ONE INCLINED FLAT HYDROPHILIC SURFACE POSITIONED TO RECEIVE EFFLUENT FROM SAID ORGAN AND PERFUSATE SUPPLIED BY SAID SECOND CONDUIT, AND MEANS FOR SUPPLYING OXYGEN CONTAINING GAS TO THE INTERIOR OF SAID CHAMBER FOR CONTACT WITH PERFUSATE ON SAID HYDROPHILIC SURFACE.
137 Citations
1 Claim
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1. APPARATUS FOR PRESERVATION OF ISOLATED VIABLE ORGANS BY HYPOTHERMIC PERFUSION, COMPRISING AN ORGAN HOLDING CHAMBER, PUMPING MEANS FOR CIRCULATING OF A PERFUSATE HAVING A FIRST CONDUIT FOR ADMINISTERING PERFUSATE TO AN ARTERY OF AN ORGAN CONTAINED IN THE CHAMBER AND A SECOND CONDUIT IN COMMUNICATION WITH SAID FIRST CONDUIT AND WITH THE INTERIOR OF SAID CHAMBER FOR SUPPLYING PERFUSATE OVER THE OUTER SURFACE OF SAID ORGAN, VALVE MEANS FOR REGULATING THE PRESSURE OF SAID PERFUSATE BEING ADMINISTERED TO SAID ORGAN, HEAT EXCHANGER MEANS FOR COOLING THE PERFUSATE, A GAS-LIQUID FILM CONTACT OXYGENATOR CONTAINED IN SAID CHAMBER, SAID OXYGENATOR COMPRISING AT LEAST ONE INCLINED FLAT HYDROPHILIC SURFACE POSITIONED TO RECEIVE EFFLUENT FROM SAID ORGAN AND PERFUSATE SUPPLIED BY SAID SECOND CONDUIT, AND MEANS FOR SUPPLYING OXYGEN CONTAINING GAS TO THE INTERIOR OF SAID CHAMBER FOR CONTACT WITH PERFUSATE ON SAID HYDROPHILIC SURFACE.
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