4-PYRIDYL SUBSTITUTED 1,4-DIHYDROPYRIDINES
First Claim
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2. A compound according to claim 1 wherein R is hydrogen or methyl, R1 is methyl, R2 is methyl, ethyl, diethyl, Beta -methoxyethyl, propargyl or furfuryl, R3 is pyridyl and R4 is methyl.
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Abstract
1,4-Dihydropyridines substituted at position 4 by pyridyl or alkyl substituted pyridyl. The said products exhibit a nitritelike effect on the heart and have utility as coronary dilators, anti-fibrillators, vascular-spasmolytics, muscular-spasmolytics and anti-hypertensives.
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4 Claims
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2. A compound according to claim 1 wherein R is hydrogen or methyl, R1 is methyl, R2 is methyl, ethyl, diethyl, Beta -methoxyethyl, propargyl or furfuryl, R3 is pyridyl and R4 is methyl.
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3. The compound according to claim 1 which is 4-(2'"'"''"'"'-pyridyl)-2,6-dimethyl-3-aceto-1,4-dihydropyridine-5-carboxylic acid ethyl ester.
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4. The compound according to claim 1 which is 4-(3'"'"''"'"'-pyridyl)-2,6-dimethyl-3-aceto-1,4-dihydropyridine-5-carboxylic acid ethyl ester.
Specification
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Current AssigneeFriedrich Bossert, Wulf Vater
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Original AssigneeFriedrich Bossert, Wulf Vater
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InventorsBossert, Friedrich, Vater, Wulf
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Primary Examiner(s)Rotman, Alan L.
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Application NumberUS05/344,344Time in Patent Office669 DaysField of Search260/295.5RUS Class Current546/257CPC Class CodesC07D 401/04 directly linked by a ring-m...
