Liquid control solution

• US 3,920,580 A
• Filed: 07/12/1973
• Issued: 11/18/1975
• Est. Priority Date: 07/12/1973
• Status: Expired due to Term

• Current Assignee: Raymond L. Mast
• Original Assignee: Raymond L. Mast
• Inventors: Mast, Raymond L.
• Primary Examiner(s): Padgett, Benjamin R.
• Assistant Examiner(s): Gron, T. S.
• Application Number:
  US05/378,687
• Time in Patent Office: 859 Days
• Field of Search: 252/408 23/23B,23M,253TP 195/13.5C 424/2,101,80,78
• US Class Current: 436/14
• CPC Class Codes: C12Q 1/54 involving glucose or galactose
• CPC Class Codes: Y10S 435/803 Physical recovery methods, e.g. chromatography, grinding
• CPC Class Codes: Y10T 436/104998 Glucose, ketone, nitrate standard or control
• CPC Class Codes: Y10T 436/105831 Protein or peptide standard or control [e.g., hemoglobin, etc.]
• CPC Class Codes: Y10T 436/108331 Preservative, buffer, anticoagulant or diluent

Abstract

A stable liquid control solution useful with dry reagent strips which strips are for determining whether or not glucose is present in blood or serum. The control solution comprising water, an antidiffusing agent and glucose. The antidiffusing agent may be selected from materials such as polyvinylpyrrolidone, polyvinyl alcohol, polyethylene glycol, dextran and bovine serum albumin. The control solution may also include adjuvants such as preservatives, common salts, dyes, colored latex particles, etc.

Claims

1. A STABLE LIQUID CONTROL SOLUTION INCLUDING A PREDETERMINED AMOUNT OF GLUCOSE FOR USE IN DETERMINING THE VALIDITY OF A DRY REAGENT STRIP CAPABLE OF INDICATING AMOUNTS OF GLUCOSE IN BLOOD OR BLOOD SERUM WHICH SOLUTION EMULATES WHOLE BODY OR BLOOD SERUM USED WITH SAID STRIP, THE SOLUTION COMPRISING WATER, GLUCOSE, A PRESERVATIVE AND BETWEEN ABOUT 3 AND 35 PERCENT BY WEIGHT OF AN ANTIDIFFUSING AGENT SELECTED FROM THE GROUP CONSISTING OF POLYVINYLPYRROLIDONE, POLYVINYL ALCOHOL, POLYETHYLENE GLYCOL DEXTRAN AND BOVINE SERUM ALBUMIN.

2. The solution of claim 1 in which said antidiffusing agent is polyvinylpyrrolidone.

3. The solution of claim 1 in which said antidiffusing agent is polyethylene glycol.

4. The solution of claim 1 in which said antidiffusing agent is dextran.

5. The solution of claim 1 in which said preservative is present in an amount between about 0.01 and 0.3 percent by weight.

6. The solution of claim 1 which additionally includes a common salt.

7. The solution according to claim 6 in which said common salt is sodium chloride.