Ballistic animal implant

• US 3,948,263 A
• Filed: 08/14/1974
• Issued: 04/06/1976
• Est. Priority Date: 08/14/1974
• Status: Expired due to Term

• Current Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Original Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Inventors: Drake, James F. Jr., Paul, Fred R. Jr.
• Primary Examiner(s): Medbery, Aldrich F.
• Application Number:
  US05/497,462
• Time in Patent Office: 601 Days
• Field of Search: 128/260, 128/268, 128/271, 128/217, 102/92 R, 102/92.7
• US Class Current: 424/422
• CPC Class Codes: A61D 7/00 Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals for reproduction or fertilisation A61D19/00 ; devices for implanting pellets, radon seeds or the like A61M37/0069
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: F42B 12/54 by implantation, e.g. hypodermic projectiles

Abstract

Ballistically implantable projectile adapted to carry biologically active materials into a living animal body and thereafter to provide sustained release of said biologically active material into said living animal body.

Claims

1. A means for providing controlled sustained release of a biologically active material comprising a ballistic implant shaped for ballistically penetrating the epidermal covering of a live animal body and lodging totally within the tissues of the animal body, said implant comprising a ballistic-shaped, biologically compatible polymer body containing therein at least one biologically active material, said biologically active material being separated from the exterior of said ballistic implant by a material defining a means for providing controlled sustained release of said biologically active material to the tissue of the animal body when exposed to the fluids and cells of said living animal body.

2. A ballistic implant according to claim 1 wherein said biologically active material is distributed within a release sustaining matrix of material which is soluble in the fluids of a living animal body.

3. A ballistic implant according to claim 2 wherein said release-sustaining matrix is carried in a cavity opening to the rear of said ballistic implant.

4. A ballistic implant according to claim 2 wherein said release-sustaining matrix consists essentially of an organic compound selected from the group consisting of gelatin, hydroxypropyl cellulose, glycerides, and beeswax.

5. A ballistic implant according to claim 1 wherein said biologically active material is at least partially enclosed by a material which is insoluble in, but permeable to the fluids of a live animal body.

6. A ballistic implant according to claim 5 wherein said insoluble, permeable material is a microporous membrane.

7. A ballistic implant according to claim 1 wherein said polymer body comprises a plastic material.

8. A ballistic implant according to claim 1 wherein said polymer body is soluble in the fluids of a living animal body and said biologically active material is distributed throughout the said polymer body.