Topical application of cis of trans 3,4-thiolanediol to reduce the greasy appearance of hair and skin

• US 3,950,532 A
• Filed: 05/10/1972
• Issued: 04/13/1976
• Est. Priority Date: 05/14/1971
• Status: Expired due to Term

• Current Assignee: L'Oreal SA
• Original Assignee: L'Oreal SA
• Inventors: Colin, Michel, Bouillon, Claude
• Primary Examiner(s): Goldberg, Jerome D.
• Assistant Examiner(s): Clark, Vera C.
• Application Number:
  US05/251,884
• Time in Patent Office: 1,434 Days
• Field of Search: 260/332.1, 260/332.3 R, 424/275, 424/DIG. 4, 252/106, 252/107
• US Class Current: 514/445
• CPC Class Codes: A61K 8/4986 with sulfur as the only hetero atom
• CPC Class Codes: A61Q 19/008 Preparations for oily skin
• CPC Class Codes: A61Q 5/006 Antidandruff preparations
• CPC Class Codes: C07D 333/32 Oxygen atoms
• CPC Class Codes: C07D 333/48 by oxygen atoms
• CPC Class Codes: Y10S 424/01 Aerosol hair preparation
• CPC Class Codes: Y10S 424/02 Resin hair settings
• CPC Class Codes: Y10S 424/04 Dandruff

Abstract

A composition and method for treating the hair and skin characterized by a greasy, unaesthetic appearance to reduce or essentially eliminate this greasy appearance which includes topically applying to a human having hair or skin so characterized a cosmetic composition containing as an active ingredient a cis or trans 3,4-thiolannediol, its cis or trans S-oxide derivatives or its cis or trans S-dioxide derivatives.

Claims

1. A process to combat dandruff and to eliminate a greasy appearance of the hair and scalp of a person having hair and scalp so characterized comprising topically applying to the hair an effective amount of a composition comprising a nontoxic carrier comprising a member selected from the group consisting of water and a dilute aqueous lower alkanol solution and an active compound of the formula ##SPC8##

wherein

X is selected from the group consisting of S, SO and SO₂, and

R₁ is selected from the group consisting of

a. H, in which case R₂ is OH, and

b. OH, in which case R₂ is H,

said active compound being present in an amount effective to combat dandruff and to eliminate said greasy appearance of the hair and scalp.

2. The process of claim 1 wherein said active compound is selected from the group consisting of

cis and trans 3,4-thiolannediol,

cis and trans 3,4-thiolannediol S-oxide, and

cis and trans 3,4-thiolannediol S-dioxide.

3. The process of claim 1 wherein said composition contains 0.5 - 20 weight percent of said active compound and said composition is applied to the hair in an amount of 15 - 20 cc by massaging.

4. A composition to combat dandruff and to eliminate a greasy appearance of the hair comprising0.5 - 20 percent by weight of an active compound of the formula ##SPC9##

wherein

X is selected from the group consisting of --S--, --SO-- and --SO₂ --, and

R₁ is selected from the group consisting of

a. H, in which case R₂ is OH and

b. OH, in which case R₂ is H;

6. The composition of claim 4 wherein X is --S--.

7. The composition of claim 4 wherein X is --SO--.

8. The composition of claim 4 wherein said active compound is present in an amount of 1 - 10 weight percent.

11. The composition of claim 8 wherein X is --S--.

12. The composition of claim 8 wherein X is --SO--.

13. The composition of claim 8 wherein said active compound is present in an amount of 1 - 10 weight percent.

14. The composition of claim 8 wherein said detergent is present in an amount of 5 - 7 weight percent.

5. from 1 to 20 weight percent of a cosmetic film forming resin having a molecular weight ranging from about 10,000 - 70,000;

and

3. a carrier selected from the group consisting of water and a dilute aqueous lower alkanol solution having a concentration of 0 - 70 weight percent of said lower alkanol.

9. A composition to combat dandruff and to eliminate a greasy appearance of the hair comprising0.5 - 20 weight percent of an active compound of the formula ##SPC10##

wherein

X is selected from the group consisting of --S--, --SO-- and --SO₂ --, and

R₁ is selected from the group consisting of

a. H, in which case R₂ is OH and

b. OH, in which case R₂ is H;

10. from 4 - 15 weight percent of a detergent selected from the group consisting of an anionic, cationic, amphoteric and nonionic detergent;

and

3. a carrier selected from the group consisting of water and a dilute aqueous lower alkanol solution said composition having a pH between 3 - 8.