Biological test apparatus

• US 3,960,499 A
• Filed: 02/18/1975
• Issued: 06/01/1976
• Est. Priority Date: 02/18/1975
• Status: Expired due to Term

• Current Assignee: Nunc A/S (Fisher Bioimage APS)
• Original Assignee: Miles Laboratories, Inc. (Bayer AG)
• Inventors: White, Fred K.
• Primary Examiner(s): Mack, John H.
• Assistant Examiner(s): Prescott, A. C.
• Application Number:
  US05/550,603
• Time in Patent Office: 469 Days
• Field of Search: 204/180 R, 204/180 G, 204/180 S, 204/299, 23/253 R, 210/31 C, 210/198 C
• US Class Current: 422/401
• CPC Class Codes: G01N 27/44704 Details; Accessories
• CPC Class Codes: G01N 27/44747 Composition of gel or of carrier mixture
• CPC Class Codes: G01N 33/558 using diffusion or migration of antigen or antibody immunochromatographic test strips G01N33/54387

Abstract

An improved biological test apparatus has an organoplastic support surface which has been treated to become hydrophilic, said surface supporting an aqueous gel employed for the desired test mechanism. The hydrophilic treatment enables the aqueous gel to be in uniform close adherent contact with the support surface. This prevents the formation of an uneven gel thickness and improves the adherence of the gel to the support surface during storage and subsequent use.

Claims

1. Biological test apparatus comprising an organoplastic support surface which has been treated to become hydrophilic and an aqueous gel in uniform

2. Apparatus according to claim 1 wherein the hydrophilic organoplastic

3. Apparatus according to claim 1 wherein the aqueous gel is an agarose

4. Apparatus according to claim 1 wherein the organoplastic support surface is formed from material selected from the class consisting essentially of polystyrene, polypropylene, styrene-acrylonitrile copolymers, polycarbonate, cellulose acetate propionate, cellulose acetate butyrate, nitrile-acrylonitrile-styrene copolymers, polyacrylate, polymethacrylate,

5. Apparatus according to claim 1 wherein the hydrophilic surface is obtained by electric discharge treatment of the organoplastic material.

6. Apparatus according to claim 1 wherein the hydrophilic surface is

7. Apparatus according to claim 1 wherein sulfate radicals are introduced

8. Apparatus according to claim 1 wherein oxygen atoms are introduced at the carbon-carbon double bond positions of the organoplastic surface molecules to form an oxirane structure which renders the surface hydrophilic.