Oral hygiene compositions

• US 3,966,863 A
• Filed: 12/04/1974
• Issued: 06/29/1976
• Est. Priority Date: 12/04/1974
• Status: Expired due to Term

• Current Assignee: Beecham Group PLC (GSK plc)
• Original Assignee: Beecham Group PLC (GSK plc)
• Inventors: Duke, Susan Ann, Forward, Geoffrey Charles, Bell, Melissa Anne
• Primary Examiner(s): Gotts, Lewis
• Assistant Examiner(s): Owens, Cary
• Application Number:
  US05/529,567
• Time in Patent Office: 573 Days
• Field of Search: 424/49-52
• US Class Current: 424/52
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/21 Fluorides; Derivatives thereof
• CPC Class Codes: A61K 8/24 Phosphorous; Compounds thereof
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

Oral hygiene compositions of enhanced anti-cariogenic activity such as toothpaste containing a calcium carbide abrasive and a combination of an ionic fluoride and an ionic monofluorophosphate in amounts to provide, respectively, from 40-80% and 20-60% of the total fluorine content of the composition.

Claims

1. An oral hygiene composition comprising:

(a) a calcium carbonate abrasive;

(b) an ionic fluoride; and

(c) an ionic monofluorophosphate, the weights of the said ingredients (b) and (c) being sufficient to provide respectively from 40-80% and 20-60% of the total fluorine content of the compositions.

2. An oral hygiene composition as claimed in claim 1 wherein ingredients (b) and (c) provide respectively 40-55% and 45-60% of the total fluorine content of the composition.

3. An oral hygiene composition as claimed in claim 1 wherein the total fluorine content is from 0.025% to 0.2% by weight of the composition.

4. An oral hygiene composition as claimed in claim 3 wherein the total fluorine content is from 0.05 to 0.12% by weight of the composition.

5. An oral hygiene composition as claimed in claim 1 in the form of a cored or striped dentifrice having an opaque core or stripes containing the calcium carbonate abrasive respectively enclosed within or laid upon a transparent gel.

6. An anti-cariogenic dentifrice having enhanced anti-cariogenic effect and comprising a polishing amount of calcium carbonate abrasive and a mixture of an ionic fluoride which produces fluoride ions in aqueous solution and an ionic monofluorophosphate, the fluoride and monofluorophosphate being present in the dentifrice in an amount to provide a total of from 0.025% to 0.2% of fluorine, based on the weight of the dentifrice, of which the fluoride provides 40-55% and the monofluorophosphate provides 45-60%.

7. An anti-cariogenic dentifrice according to claim 6 wherein the ionic fluoride is an alkali metal fluoride and the ionic monofluorophosphate is an alkali metal monofluorophosphate.

8. An anti-cariogenic dentifrice according to claim 7 wherein the ionic fluoride and the ionic monofluorophosphate are present in about equal proportions.