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8-Substituted cyclic nucleotides by free radical alkylation and acylation

  • US 3,968,101 A
  • Filed: 12/20/1974
  • Issued: 07/06/1976
  • Est. Priority Date: 12/20/1974
  • Status: Expired due to Term
First Claim
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1. The compound of the structure:

  • ##SPC4##wherein X is H or NH2 ; and

    R'"'"' is iso-propyl;

    neo-pentyl;

    C1 to C8 substituted alkyl wherein the alkyl is substituted at the 1-alkyl position and the substituents are selected from the group consisting of hydroxyl, phenyl, semicarbazone, thiosemicarbazone, 4-phenyl semicarbazone, and phenyl hydrazone;

    benzyl;

    C1 to C8 acyl;

    or carbamoyl.

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