Method and apparatus for dual resolution analysis of a scene

• US 3,970,841 A
• Filed: 11/25/1974
• Issued: 07/20/1976
• Est. Priority Date: 11/25/1974
• Status: Expired due to Term

• Current Assignee: James E. Green
• Original Assignee: James E. Green
• Inventors: Green, James E.
• Primary Examiner(s): La Roche, Eugene
• Application Number:
  US05/526,896
• Time in Patent Office: 603 Days
• Field of Search: 356/39, 356/40, 250/578, 250/548, 250/201, 250/203, 250/208, 250/209, 250/222 PC, 235/92 PC, 350/37, 350/40
• US Class Current: 250/548
• CPC Class Codes: G01N 15/1468 with spatial resolution of the texture or inner structure of the particle
• CPC Class Codes: G02B 21/18 Arrangements with more than one light path, e.g. for comparing two specimens
• CPC Class Codes: G02B 21/361 Optical details, e.g. image relay to the camera or image sensor G02B21/364 takes precedence; illumination details G02B21/06 and subgroups
• CPC Class Codes: G06V 20/69 Microscopic objects, e.g. biological cells or cellular parts

Abstract

A method and apparatus for analyzing a scene at a low resolution until an object of interest is detected. Thereafter, the object of interest is analyzed at a higher resolution while continuing to analyze the scene at the low resolution. In the preferred embodiment, the scene compromises a blood sample and the objects of interest are blood cells.

Claims

1. A dual resolution sample scanning apparatus comprising:

means for positioning a sample;

a first opto-electrical image scanning means producing an output signal when a sample object is encountered during scanning;

a second opto-electrical image scanning means for producing output signals representative of a scanned image;

optical means for imaging a low resolution sample field on said first opto-electrical image scanning means and a higher resolution sample field on said second opto-electrical image scanning means;

means responsive to the output signal from said first opto-electrical image scanning means for moving the higher resolution sample field relative to the sample to bring the encountered sample object into the higher resolution field for scanning by said second opto-electrical image scanning means while the first opto-electrical image scanning means continues to scan the low resolution field to detect any other objects in the sample, said continuing low resolution field scan being performed without moving the sample relative to at least one of said resolution fields; and

,

utilization means responsive to the output signals from said second opto-electrical image scanning means.

2. The apparatus of claim 1 wherein said sample positioning means includes an X-Y movable sample support means and said output signal responsive moving means includes X and Y drive means for moving said sample support means.

3. The apparatus of claim 1 wherein said at least one resolution field is the low resolution field.

4. The apparatus of claim 1 wherein said at least one resolution field is the higher resolution field.

5. The apparatus of claim 1 wherein said continuing low resolution scanning is performed without moving the sample relative to low and higher resolution fields.

6. The apparatus of claim 1 where said optical means for imaging said low and higher resolution sample fields has an optical path for the low resolution sample field and an optical path for the higher resolution sample fields.

7. The apparatus of claim 6 wherein said optical paths have a common portion.

8. The apparatus of claim 1 wherein said output signal responsive moving means moves both the low and higher resolution sample fields relative to the sample.

9. The apparatus of claim 8 wherein said moving means moves both the low and higher resolution sample fields relative to the sample without altering the relative relationship of the two fields with respect to each other.

10. The apparatus of claim 9 wherein the higher resolution sample field is positioned within the low sample resolution field.

11. The apparatus of claim 9 wherein the higher sample resolution field and the low sample resolution field partially overlap.

12. The apparatus of claim 9 wherein the higher resolution sample field is positioned outside of the low resolution sample field.

13. A dual resolution scanning apparatus comprising:

means for positioning a sample;

means for scanning a positioned sample at a low resolution, said low resolution scanning means having a low resolution field of view;

means for detecting when a sample object is encountered during the low resolution scan;

means for scanning an encountered object at a higher resolution, said higher resolution scanning means having a higher resolution field of view;

means responsive to said object detection means for initiating the object scanning by said high resolution scanning means while said low resolution scanning means continues to scan the sample to detect any other objects in the sample without moving the sample relative to at least one of said resolution fields of view.

14. The apparatus of claim 13 wherein said at least one resolution field is the low resolution field.

15. The apparatus of claim 13 wherein said at least one resolution field is the higher resolution field.

16. The apparatus of claim 13 wherein said continuing low resolution scanning is performed without moving the sample relative to low and higher resolution fields.

17. A method for dual resolution scanning of a sample comprising the steps of:

scanning a low resolution field of the sample until an object is detected; and

thereafter,

scanning a higher resolution field containing the detected object while continuing scanning of the low resolution field to detect any other objects in the sample, said continuing low resolution scanning being performed without moving the sample relative to at least one of said resolution fields.

18. The method of claim 17 wherein said at least one resolution field is the low resolution field.

19. The method of claim 17 wherein said at least one resolution field is the higher resolution field.

20. The method of claim 17 wherein said continuing low resolution scanning is performed without moving the sample relative to low and higher resolution fields.

21. The method of claim 17 further comprising the step of moving the higher resolution field relative to the sample to bring each detected object into the higher resolution field.

22. The method of claim 21 further comprising the step of moving both the low and higher resolution fields relative to the sample while maintaining the same relative position with respect to each other.