Benzofuran derivatives

• US 3,974,172 A
• Filed: 02/06/1974
• Issued: 08/10/1976
• Est. Priority Date: 02/09/1973
• Status: Expired due to Term

• Current Assignee: Hoechst Aktiengesellschaft (Sanofi )
• Original Assignee: Hoechst Aktiengesellschaft (Sanofi )
• Inventors: Rosch, Gunter, Schinzel, Erich, Sahm, Wilfried
• Primary Examiner(s): Rush, Raymond V.
• Application Number:
  US05/440,013
• Time in Patent Office: 916 Days
• Field of Search: 260/307 D
• US Class Current: 548/224
• CPC Class Codes: C07D 307/79 with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
• CPC Class Codes: C07F 9/1651 with hydroxyalkyl compounds with further substituents on alkyl
• CPC Class Codes: C07F 9/65324 condensed with carbocyclic rings or carbocyclic ring systems

Abstract

Benzofuran compounds of the formula ##SPC1##

Wherein E is a bivalent bridging member of the formula ##SPC2##

S is hydrogen, halogen, lower alkyl, carboxy, sulfo, cyano, lower carboalkoxy, carbonamido, lower mono- or dialkyl carbonamido, sulfonic acid lower alkyl ester, sulfonamido, lower mono- or dialkyl sulfonamido or phenyl; P, Q, T and U are hydrogen or halogen, lower alkyl, lower alkoxy, phenyl, carboxy, cyano, lower carboalkoxy, lower carbo-alkoxy substituted by a member selected from the group consisting of lower alkoxy, lower dialkylamino and lower trialkyl ammonium, carbonamido, lower mono- or di-alkyl carbonamido, sulfo, sulfonic acid lower alkyl ester, sulfonamido or lower mono- or dialkyl sulfonamido or P and Q together or T and U together are lower alkylene or an annellated phenyl ring, and n is 1 to 3. These compounds can be synthetized by a condensation reaction of the corresponding carboxylic acid derivative with an ortho-aminophenol or by HORNER or similar syntheses forming said bridging member. The products are optical brighteners.

Claims

1. A compound of the formula ##SPC24##

wherein E is p-phenylene and T is selected from the group consisting of 5-(β

-dimethylamino)-carboethoxy and 5-(β

-trimethylammonium)-carbo-ethoxy methosulfate.

2. The compound of claim 1 wherein R is 5-(β

-trimethylammonium)-carbo-ethoxy methosulfate.