Gas sampling catheter assembly and method

• US 3,981,297 A
• Filed: 03/03/1975
• Issued: 09/21/1976
• Est. Priority Date: 03/03/1975
• Status: Expired due to Term

• Current Assignee: Sorenson Research Company Incorporated
• Original Assignee: Sorenson Research Company Incorporated
• Inventors: Reynolds, Gordon S., Dunn, Karl L.
• Primary Examiner(s): Howell, Kyle L.
• Application Number:
  US05/555,007
• Time in Patent Office: 568 Days
• Field of Search: 128/2 E, 128/2 G, 128/2 L, 128/2 M, 128/2 R, 128/349, 128/348, 128/214 R, 128/214.4, 73/23 P, 73/1 R, 73/421.5 R
• US Class Current: 600/364
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61M 25/0021 characterised by the form of the tubing A61M25/0054 takes precedence
• CPC Class Codes: A61M 25/0023 by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/008 Strength or flexibility characteristics of the catheter tip

Abstract

A catheter assembly for sampling gases in biological tissue in vivo, including a catheter constructed of a hollow tube sheathed in a gas-permeable membrane, and an impermeable barrier between the tube and membrane to define the boundary of a sampling tip. A catheter hub slideably surmounts the catheter and detachably receives a calibration chamber normally surrounding the sampling tip. The method includes purging the calibration chamber with a calibration gas and thereafter removing the calibration chamber and inserting the catheter into the tissue to be sampled.

Claims

1. A catheter for sampling gases in vivo comprising:

a hollow generally flexible gas-impermeable tube having a leading end at least a portion of which is adapted to be inserted into the body of a patient;

a gas-permeable membrane traversing the entire length of the insertable portion of the tube;

means at the leading end of the tube for communicating the hollow of the tube and the inside of the gas-permeable membrane; and

a gas-impervious barrier means circumscribing the tube between the tube and membrane behind the communicating means to prevent gas transfer to the leading end from membrane behind the barrier.

2. A catheter assembly for sampling gases in vivo comprising:

a hollow gas-impermeable tube terminating in a tip insertable into the body of a patient;

a gas-permeable membrane circumscribing the tip and the entire insertable portion of the tube;

communication means associated with the insertable tip and providing communication between the inside of the insertable tip and the gas-permeable membrane;

a gas-impervious barrier means interposed between the membrane and the tube adjacent the tip;

a catheter hub, slideably surmounting the tube and membrane normally situated rearward of the tip, the hub comprising coupling means; and

a diametrally enlarged calibration chamber removably mounted upon the coupling means and surrounding the catheter tip, the calibration chamber having a port for admitting calibration gases into the space around the catheter tip confined by the calibration chamber.

3. A catheter assembly as defined in claim 2 wherein said catheter hub comprises an interior guide through which the tube is axially displaced, the guide being diametrally reduced at the leading end of the hub to make friction contact with the membrane-covered tube.

4. A catheter assembly for sampling gases as defined in claim 2 further comprising an elongated conduit circumscribing that portion of the membrane-covered tube located rearward of the catheter hub, the conduit having a longitudinal slit which is automatically opened at the catheter hub to separate the membrane-covered tube from the conduit when the conduit is advanced through the hub.

5. A catheter assembly as defined in claim 2 further comprising a solid base rigidly mounted upon the hollow tube, the base revealing sufficient tube length to permit attachment to a conventional gas analyzer.

6. A catheter assembly as defined in claim 2 wherein said calibration chamber comprises a filter situated near the inlet port to filter calibration gases before the calibration gases reach the tip of the gas-permeable membrane.

7. A catheter assembly as defined in claim 2 wherein said calibration chamber comprises at least one discharge port to permit the interior of the calibration chamber to be purged with calibration gas.

8. A catheter assembly as defined in claim 2 wherein the communication means associated with the insertable tip of the gas impermeable tube comprises at least one surface interruption exposing the inside of the circumscribing membrane to the interior of the tube.

9. A catheter assembly for sampling gases comprising:

an elongated tube comprising an exterior gas-permeable membrane, the leading end of the tube comprising a sampling tip;

means communicating the inside of the sampling tip with the gas-permeable membrane;

a calibration chamber having an internal diameter which is greater than the external diameter of the sampling tip, the calibration chamber removably surrounding the sampling tip; and

means mounted upon the calibration chamber for communicating calibration gas to the interior of the calibration chamber thereby immersing the sampling tip in calibration gas having a known gas composition.

10. A catheter assembly as defined in claim 9 further comprising means mounted upon the calibration chamber for filtering contaminants from the calibration gas before the calibration gas reaches the sampling tip.

11. A method of sampling gases comprising the steps of:

obtaining a gas sampling tube and covering the tube with a gas-permeable membrane, the tube having an opening at the tip thereof which opening is exposed to the membrane;

providing a gas-impervious barrier between the tube and membrane near the tip of the tube so as to define a sampling tip of predetermined length;

surrounding the sampling tip with a removable calibration chamber;

admitting a predetermined gas into the calibration chamber around the sampling tip to accommodate calibration of the catheter prior to in vivo sampling; and

thereafter situating the catheter adjacent tissue to be sampled.

12. A method of sampling gases as defined in claim 11 further comprising:

surrounding at least a portion of the length of the tube with a conduit, the conduit having a longitudinal slit therein; and

slideably surmounting a hub upon the tube, the hub cooperating with the conduit to simultaneously open the conduit and separate the tube therefrom as the tube is advanced through the hub.