Ferromagnetic separation process and material
First Claim
1. A process of conveying a solid from one container to another comprising:
- placing a plurality of particles of a ferromagnetic substance in a test tube;
moving a magnet near the outer surface of the first tube near the bottom end thereof;
placing a collar over the open end of the tube; and
moving the magnet upwardly along the tube to a point above the upper opening of the tube whereby the particles of a ferromagnetic substance and any substance entrapped thereby are moved into the collar.
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Accused Products
Abstract
A method of carrying out a solid phase chemical reaction or a filtration step to remove a solid from a liquid utilizing ferromagnetic particles. The particles may have a porous or otherwise bondable solid support material having adsorbed or chemically bonded thereon a biologically active substance to make them biologically active. Alternatively, the particles may act as an inert medium to convey a solid precipitate out of a liquid. The process involves the addition of the ferromagnetic particles to a potentially reactive fluid. After the fluid has reacted either as a result of contact with the biologically active material or by a process causing a precipitate in the fluid, the particles may be separated from the fluid by bringing the particles into close proximity with a magnet such as an electromagnet. When sufficient particles are held in an elongated container and a magnetic force is exerted to hold the particles in a porous mass across the container, the particles may be moved through the liquid to filter solid particles from the liquid. A second container may be placed over a portion of the elongated container on the particles and any entrapped precipitate may be removed from the elongated container. The particles may alternatively have a bondable surface capable of adsorption or chemical coupling of biologically active materials. Polymer and ceramic biomaterial supports and particular combinations with ferromagnetic materials are disclosed. A valve formed from the ferromagnetic particles is also disclosed herein.
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Citations
11 Claims
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1. A process of conveying a solid from one container to another comprising:
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placing a plurality of particles of a ferromagnetic substance in a test tube; moving a magnet near the outer surface of the first tube near the bottom end thereof; placing a collar over the open end of the tube; and moving the magnet upwardly along the tube to a point above the upper opening of the tube whereby the particles of a ferromagnetic substance and any substance entrapped thereby are moved into the collar. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A process for conveying a solid from one container to another comprising:
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placing a plurality of particles of a ferromagnetic substance in a first test tube; moving a magnet near the outer surface of the first test tube near the bottom thereof; placing a second tube over the open end of the first tube; and moving the magnet upwardly along the first tube to a point above the upper opening of the first tube whereby the magnetic particles and any substance entrapped thereby are moved into the second tube.
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Specification