Apparatus for proton radiography

• US 3,986,026 A
• Filed: 11/14/1975
• Issued: 10/12/1976
• Est. Priority Date: 11/14/1975
• Status: Expired due to Term

• Current Assignee: The United States of America as represented by the United States Energy Research and Development Administration
• Original Assignee: The United States of America as represented by the United States Energy Research and Development Administration
• Inventors: Martin, Ronald L.
• Primary Examiner(s): Borchelt, Archie R.
• Application Number:
  US05/632,030
• Time in Patent Office: 333 Days
• Field of Search: 250/306, 250/307, 250/358 R, 313/359, 313/363, 328/235
• US Class Current: 250/306
• CPC Class Codes: A61B 6/00 Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment instruments measuring radiation intensity for application in the field of nuclear medicine, e.g. in vivo counting, G01T1/161; apparatus for taking X-ray photographs G03B42/02
• CPC Class Codes: A61B 6/4092 for producing synchrotron radiation
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: G01N 23/04 and forming images of the material

Abstract

An apparatus for effecting diagnostic proton radiography of patients in hospitals comprises a source of negative hydrogen ions, a synchrotron for accelerating the negative hydrogen ions to a predetermined energy, a plurality of stations for stripping extraction of a radiography beam of protons, means for sweeping the extracted beam to cover a target, and means for measuring the residual range, residual energy, or percentage transmission of protons that pass through the target. The combination of information identifying the position of the beam with information about particles traversing the subject and the back absorber is performed with the aid of a computer to provide a proton radiograph of the subject. In an alternate embodiment of the invention, a back absorber comprises a plurality of scintillators which are coupled to detectors.

Claims

1. An apparatus for performing diagnostic proton radiography of a human subject comprising:

a source of negative hydrogen ions;

a synchrotron connected to the source to receive the negative hydrogen ions and accelerate them in an orbit to a precisely controlled predetermined value of energy;

means connected to the synchrotron for stripping the accelerated negative hydrogen ions to produce a beam of protons and extract the beam from the synchrotron;

means for disposing the human subject in the beam of protons;

means for sweeping the beam of protons in a predetermined pattern to traverse a portion of the human subject;

a proton detector disposed to receive the portion of the beam that traverses the human subject and to detect a parameter of the protons received thereat; and

display means connected to the sweeping means and the detecting means to produce from information about beam position and beam intensity a proton radiograph of the subject.

2. The apparatus of claim 1 wherein the means for stripping comprise:

a bumping magnet coupled to the accelerated beam and responsive to a current to change the orbit of the accelerated beam; and

a fixed foil stripper disposed at the edge of the accelerated beam in a location such that a change in the orbit in response to a current in the bumping magnet moves the beam into contact with the fixed foil stripper to remove electrons from the negative hydrogen ions and convert them to protons.

3. The apparatus of claim 1 wherein the proton detector comprises:

a beam stop of organic material disposed in the beam that traverses the human subject to absorb all protons below a predetermined value of energy;

a scintillator disposed in the beam that has traversed the beam stop to detect protons traversing the subject and the beam stop; and

a photomultiplier coupled optically to the scintillator to generate an electric signal in response to scintillations therein.

4. The apparatus of claim 1 wherein the proton detector comprises:

a plurality of scintillators disposed sequentially in the beam that has traversed the human subject, and a plurality of photomultipliers each coupled optically to one of said scintillators and generating an electric signal in response to scintillations therein, which electric signal is a function of the parameters of the beam of protons passing through said scintillator.

5. The apparatus of claim 1 wherein the display means comprise:

a computer to store information about proton count as a function of beam position and means for making a plot of proton count as a function of beam position, which plot is a proton radiograph of the human subject.

6. The apparatus of claim 1 wherein the means for disposing the human subject comprises a fixed support.

7. The apparatus of claim 1 wherein the means for disposing the human subject comprise a rotating support.

10. The apparatus of claim 1 wherein the proton detector comprises:

a plurality of scintillators disposed sequentially in the beam that has traversed the object, and a plurality of photomultipliers each coupled optically to one of said scintillators and generating an electric signal in response to scintillations therein, which electric signal is a function of the parameters of the beam of protons passing through said scintillator.

8. An apparatus for making proton radiographs of an object comprising:

a source of negative hydrogen ions;

a synchrotron connected to the source to receive the negative hydrogen ions and accelerate them in an orbit to a precisely controlled predetermined value of energy of the order of 200 MeV;

means connected to the synchrotron for stripping the accelerated negative hydrogen ions to produce a beam of protons and extract the beam from the synchrotron;

means for disposing the object in the beam of protons;

means for sweeping the beam of protons in a predetermined pattern to traverse a portion of the object;

means for detecting a parameter of the beam of protons that has traversed the object;

means for generating a visual display of the parameter as a function of the predetermined pattern, which visual display is a proton radiograph of the object.

9. The apparatus of claim 8 wherein the means for stripping comprise:

a bumping magnet coupled to the accelerated beam and responsive to a current to change the orbit of the accelerated beam; and

a fixed foil stripper disposed at the edge of the accelerated beam in a location such that a change in the orbit in response to a current in the bumping magnet moves the beam into contact with the fixed foil stripper to remove electrons from the negative hydrogen ions and convert them to protons.