Non-antigenic, non-thrombogenic infection-resistant grafts from umbilical cord vessels and process for preparing and using same
First Claim
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1. A flexible, hardened segment of a mammalian umbilical cord vessel in a shape other than that in which it occurs in nature, for use as a prosthesis in mammals, said segment having vanishingly low antigenicity and thrombogenicity.
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Abstract
Arteries and veins of umbilical cords are hardened and shaped by processes described. Prostheses in the form of tubes, patches and conduits are prepared from the shaped vessels. The prostheses are used as reinforcements and replacements for vessels, ducts, intestines and urinary bladders. The processes result in products which have vanishingly low antigenicity and thrombogenicity, are resistant to infection and which may be stored indefinitely for use when needed by a surgeon.
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Citations
55 Claims
- 1. A flexible, hardened segment of a mammalian umbilical cord vessel in a shape other than that in which it occurs in nature, for use as a prosthesis in mammals, said segment having vanishingly low antigenicity and thrombogenicity.
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10. A process for preparing a prosthesis for use in surgery comprising the steps of
a. separating and removing at least one of the principal blood vessels from a mammalian umbilical cord; -
b. hardening said blood vessel by means of a reagent; c. shaping said vessel. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55)
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Specification