Seizure suppression device

• US 3,993,046 A
• Filed: 11/06/1974
• Issued: 11/23/1976
• Est. Priority Date: 11/06/1974
• Status: Expired due to Term

• Current Assignee: George T. Pardue, Heriberto Fernandez
• Original Assignee: George T. Pardue, Heriberto Fernandez
• Inventors: Pardue, George T., Fernandez, Heriberto
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US05/521,402
• Time in Patent Office: 748 Days
• Field of Search: 128/419 R, 128/421, 128/422, 128/1 C, 128/2.1 B, 128/2.1 R, 128/2.06 B, 128/2.06 R
• US Class Current: 600/545
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/372 Analysis of electroencephalograms
• CPC Class Codes: A61B 5/4094 Diagnosing or monitoring seizure diseases, e.g. epilepsy
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/7405 using sound

Abstract

A method and apparatus for suppressing epileptic seizures whereby an EEG electrical signal from an epileptic is amplified, filtered to remove components above roughly 8 Hz and below 2 Hz, and applied to a level detector which produces a trigger signal when the EEG amplitude exceeds a predetermined, variable level. The gated signal operates an oscillator to produce a signal which is in turn applied to a speaker, such as a set of earphones, to produce an audio signal which is maintained for as long as the seizure lasts, and then for an additional 4 seconds.

Claims

1. Apparatus for suppressing an epileptic seizure comprising:

electrical circuit means for receiving an EEG electrical waveform signal and producing an electrical trigger signal only when and for as long as the amplitude thereof exceeds a predetermined level with respect to a given reference level, that reference level indicating an epileptic seizure,

electrical circuit means responsive to said trigger signal for producing an oscillatory electrical signal, until said trigger signal is no longer received, and only following production of said trigger signal, and

speaker means for receiving said oscillatory signal and producing an audio signal which suppresses said seizure.

2. Apparatus as in claim 1 wherein said oscillatory signal producing means includes means for producing an audio frequency signal.

3. Apparatus as in claim 1 wherein said speaker means includes a set of earphones.

4. Apparatus as in claim 1 further including means for filtering out of an EEG signal components having a frequency greater than a first level and less than a second level and applying the filtered EEG signal to said receiving and trigger signal producing means.

5. Apparatus as in claim 4 wherein said filtering and applying means involves a high pass filter and a serially connected low pass filter.

6. Apparatus as in claim 4 wherein said first level is roughly 2 Hz and said second level is roughly 8 Hz.

7. Apparatus as in claim 4 further including a high impedance amplifier connected to the input to said filtering and applying means.

8. Apparatus as in claim 1 wherein said receiving and trigger signal producing means includes a level detector and wherein said oscillatory signal producing means includes a one-shot flip-flop connected to the output of said level detector and a trigger oscillator connected to the output of said flip-flop.

9. Apparatus as in claim 8 including a source of voltage and a variable resistor connected to said flip-flop for controlling the time duration of the pulse produced by said flip-flop.

10. Apparatus as in claim 8 wherein said level detector and trigger oscillator each include an operational amplifier.

11. Apparatus as in claim 8 further including an amplifier connecting said trigger oscillator to said speaker means.

12. Apparatus as in claim 8 wherein said level detector includes a differential amplifier with one input for receiving said EEG signal, a voltage source and a variable resistor connecting said voltage source to the other input of said differential amplifier.

13. Apparatus as in claim 1 wherein said oscillator signal producing means includes means for maintaining said oscillatory signal for a predetermined time following when said amplitude ceases to exceed said predetermined level.

14. Apparatus as in claim 13 wherein said oscillator signal producing means includes means for varying said predetermined time.

15. A method of suppressing epileptic seizures comprising the steps of

producing an electrical trigger signal whenever the amplitude of an electrical EEG signal exceeds a predetermined level with respect to a predetermined reference level, that reference level indicating an epileptic seizure,

producing an oscillatory electrical signal only following production of said trigger signal and

converting said oscillatory signal into an audio, seizure suppressing signal.

16. A method as in claim 15 including the further step of maintaining said oscillatory signal for a predetermined time after said amplitude ceases exceeding said predetermined level.

17. A method as in claim 15 including the further step of removing components from said EEG signal having a frequency higher than a first frequency and less than a second frequency before producing said trigger signal.