Medical bandage
First Claim
1. A medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active drugs by absorption through the external body skin or mucosa, said bandage being comprised of a laminate of:
- (1) a backing member defining one face surface of a bandage;
bearing (2) a discrete middle reservoir containing a drug confined therein;
the reservoir being formed of a material permeable to passage of drug; and
wherein one or more drug release rate controlling membranes are laminated to the surface of the reservoir so as to define the other face surface of the bandage to continuously meter the flow of a therapeutically effective amount of drug to the skin or mucosa of the patient at a predetermined rate over a period of time; and
(3) means to secure said bandage to the patient.
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Accused Products
Abstract
A bandage for continuously administering controlled quantities of systemically active drugs through the skin or mucosa is disclosed. This bandage has a backing member which defines one of its face surfaces and at least one reservoir containing the systemically active drug formulation which defines the other face surface. The reservoir can be a distinct layer of the bandage or can be a plurality of microcapsules distributed throughout a matrix. The material used to form the reservoir is drug release rate controlling and for a prolonged period continuously meters a controlled and predetermined flow of drug from the reservoir to the skin or mucosa of a patient.
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Citations
21 Claims
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1. A medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active drugs by absorption through the external body skin or mucosa, said bandage being comprised of a laminate of:
- (1) a backing member defining one face surface of a bandage;
bearing (2) a discrete middle reservoir containing a drug confined therein;
the reservoir being formed of a material permeable to passage of drug; and
wherein one or more drug release rate controlling membranes are laminated to the surface of the reservoir so as to define the other face surface of the bandage to continuously meter the flow of a therapeutically effective amount of drug to the skin or mucosa of the patient at a predetermined rate over a period of time; and
(3) means to secure said bandage to the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
- (1) a backing member defining one face surface of a bandage;
Specification