Method and apparatus for determining patient lung pressure, compliance and resistance

• US 4,031,885 A
• Filed: 10/15/1975
• Issued: 06/28/1977
• Est. Priority Date: 10/15/1975
• Status: Expired due to Term

• Current Assignee: Puritan Bennett Corp. (Medtronic Plc)
• Original Assignee: Puritan Bennett Corp. (Medtronic Plc)
• Inventors: Davis, James E. P., Omelich, David M.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US05/622,536
• Time in Patent Office: 622 Days
• Field of Search: 128/2.08, 128/145.8, 128/DIG. 17
• US Class Current: 600/533
• CPC Class Codes: A61B 5/085 Measuring impedance of respiratory organs or lung elasticity
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0033 electrical
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/46 Resistance or compliance of the lungs

Abstract

A method and appartus for determining patient lung pressure, compliance and resistance, for use in conjunction with a respirator system of the compensated-volume type wherein a predetermined volume of gas is delivered to the patient in each breathing cycle. The method and apparatus of the invention determine both the system pressure at the point of delivery to the patient and the patient lung pressure, both at the end of the inspiration phase of the breathing cycle, and utilize these values, together with a compensated volume signal, to compute the values of patient compliance and resistance. Control circuitry, actuated periodically or on demand, substitutes an enforced plateau period following inspiration, to allow the system pressure to fall to the value of lung pressure which is obtained at the end of the inspiration phase, thereby permitting the measurement of lung pressure by sampling system pressure at the end of the plateau period. The control circuitry also controls analog-to-digital converters which convert the computed values of pressure, compliance and resistance for display in a digital display device.

Claims

1. For use with a respirator system of the volume-compensated type in which a preselected volume of gas is delivered to a patient during an inspiration phase of the patient breathing cycle, apparatus for the determination of patient compliance and resistance comprising:

control means operable to initiate computation and display of patient compliance and resistance;

means for sampling the system pressure at the end of the inspiration phase;

means included within said control means for ensuring a plateau phase, following the inspiration phase and preceeding an expiration phase, long enough to allow the system pressure to equalize with the patient lung pressure;

means for sampling the system pressure at the end of the plateau phase, to obtain a measure of the lung pressure at the end of the inspiration phase;

means for monitoring the actual volume of gas delivered to the patient; and

means for computing and displaying patient compliance, as derived from the monitored volume and the system pressure sampled at the end of the inspiration phase, and patient resistance, as derived from the monitored volume and the two sampled values of the system pressure.

2. Apparatus as set forth in claim 1, wherein:

said means for computing and displaying includes digital display means and analog-to-digital converter means; and

said control means includes means for initiating operation of said analog-to-digital converter means.

3. Apparatus as set forth in claim 1, wherein said control means is able to be actuated both manually on demand and automatically on a periodic basis, to initiate operation of said apparatus.

4. Apparatus as set forth in claim 3, wherein said control means includes:

switching means to change the value of a circuit parameter temporarily and thereby to substitute a relatively long plateau phase for one normally in effect; and

switch control means for controlling operation of said switching means, and including manual means for enabling said switch control means on demand, and automatic means for enabling said switch control means automatically and periodically.

5. A method for the determination of the compliance and resistance of a patient undergoing breathing therapy from a respirator system for the delivery of a preselected volume of gas to the patient during an inspiration phase of each breathing cycle, said method comprising the steps of:

monitoring respirator system pressure during each breathing cycle, the breathing cycle including the inspiration phase, a plateau phase during which exhalation is prevented, and an expiration phase;

sampling the system pressure at the end of the inspiration phase and at the end of the plateau phase, whereby the sampled system pressure at the end of the plateau phase is substantially equal to the patient lung pressure at the end of the inspiration phase;

measuring a compensated volume of gas delivered to the patient during the inspiration phase;

differentiating the compensated volume with respect to time; and

computing the patient compliance and resistance from the measured compensated volume, its time differential and the sampled system pressure values.

6. A method as set forth in claim 5, and further including displaying the computed values in a digital display device.

7. A method as set forth in claim 5, and further including the step of substituting for an operator-selected plateau phase a plateau phase of sufficient length to ensure equalization of system and lung pressures by the end of the plateau phase.

8. A method as set forth in claim 7, and further including the steps of:

converting the computed compliance and resistance values to digital form;

displaying the converted values in a digital display device; and

initiating said steps of substituting, converting and displaying in response to an operator command and to a periodically generated starting signal.

9. A method as set forth in claim 8, wherein said steps of converting and displaying also include converting and displaying the lung pressure value.

10. Apparatus for use with a respirator system of the volume-compensated type in which a preselected volume of gas is delivered to a patient in each breathing cycle, the cylce having an inspiration phase, followed by a plateau phase during which exhalation is prevented, and an expiration phase, said apparatus being for the determination of patient compliance and resistance, and comprising:

first electrical means for computing a respirator system pressure and a patient lung pressure both at the end of the inspiration phase of the breathing cycle, said first electrical means including means for ensuring a plateau phase long enough to allow the system and lung pressures to equalize, and means for sampling system pressure at the end of the inspiration phase and at the end of the plateau phase, whereby the system pressure at the end of the plateau phase is substantially equal to the lung pressure at the end of the inspiration phase;

means for obtaining a measure of compensated volume of gas delivered to the patient during the inspiration phase; and

second electrical means for computing patient compliance from the compensated volume and the system pressure at the end of the inspiration phase, and for computing the patient resistance from the compensated volume and the system and lung pressures at the end of the inspiration phase.

11. Apparatus as set forth in claim 10, wherein said second electrical means includes:

differentiator means connected to generate a time differential of the compensated volume;

means for computing compliance by dividing the compensated volume by the lung pressure at the end of the inspiration phase; and

means for computing resistance by dividing the difference between the system and lung pressures by the time differential of the compensated volume, all measured at the end of the inspiration phase.

12. Apparatus as set forth in claim 11, wherein said second electrical means further includes means for displaying the computed values of patient compliance and resistance.

13. Apparatus as set forth in claim 12, wherein:

said first and second electrical means operate on electrical analog signals representing the various quantities of pressure and volume;

said second electrical means further include analog-to-digital conversion means for converting the computed values of compliance and resistance into digital form; and

said means for displaying the computed values of compliance and resistance is a digital display means.