Automatic chemical testing apparatus incorporating improved conveyor system

• US 4,039,288 A
• Filed: 09/21/1976
• Issued: 08/02/1977
• Est. Priority Date: 03/17/1976
• Status: Expired due to Term

• Current Assignee: Boehringer Mannheim Diagnostics Corp. (Roche Holding AG)
• Original Assignee: Boehringer Mannheim Diagnostics Corp. (Roche Holding AG)
• Inventors: Moran, John J.
• Primary Examiner(s): Serwin, R.E.
• Application Number:
  US05/725,269
• Time in Patent Office: 315 Days
• Field of Search: 23/230 R, 23/253 R, 23/259, 141/130
• US Class Current: 422/65
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 2035/0417 forming an endless chain in a vertical plane
• CPC Class Codes: G01N 35/021 having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes
• CPC Class Codes: G01N 35/1002 Reagent dispensers
• CPC Class Codes: G01N 35/1083 with one horizontal degree of freedom

Abstract

In an automatic chemical testing apparatus, a reaction loop conveyor carries rows of reaction containers in a path including an upper, forward path in a direction normal to the rows. Samples for analysis are provided to the reaction conveyor from a sample source. An improved system is provided in which sample source means synchronized with the reaction conveyor index successive sample containers to an aspiration station adjacent to one row in the forward path of the reaction conveyor. The sample source means may be a sample conveyor consisting of sample container holders linked together.

Claims

1. In a chemical testing apparatus including reaction means having a plurality of sections defining rows and each containing a plurality of reaction containers therein, said rows extending in a transverse direction and being mounted for movement in a longitudinal direction in a forward path from a beginning thereof at which aliquots of samples are dispensed into reaction containers in a first section through the forward path to readout means at which reacted contents of reaction containers are analyzed, an aspiration station transversely displaced from said reaction means and in longitudinal registration with said first section, sample source means including a plurality of sample holders, each sample holder for moving a sample, sample indexing means for indexing said sample holders to successive positions in said sample source means, means mounting said sample source means such that one position thereof is at said aspiration station, drive means for driving said sample indexing means, and control means coupled to said drive means for indexing said sample holders in synchronism with indexing of said sections in said reaction means.

2. The improvement of claim 1 wherein said sample source means comprises a conveyor and wherein said sample holders are linked together to form a conveyor.

3. The improvement according to claim 2 wherein said sample holders comprise holders for receiving tubes for containing samples.

4. The improvement according to claim 3 wherein said conveyor is mounted adjacent to said reaction means and transversely displaced to one side thereof and comprises longitudinally extending forward and return paths.

5. The improvement according to claim 4 wherein said sample holders are dimensioned and said conveyor is mounted such that samples are presented at said aspiration station in vertical registration with the group of reaction containers, whereby delivery of aliquots to the group of reaction containers is facilitated.

6. In a chemical testing apparatus including an endless loop reaction conveyor mounted in a predetermined spatial relationship to a housing, said reaction conveyor comprising a plurality of sections, each section extending in a transverse direction for movement in a longitudinal direction, and reaction containers supported in each of said sections, and means for aspirating a sample at an aspiration station and delivering to one section aliquots of the sample, the improvement comprising means defining the aspiration station transversely displaced from said reaction conveyor and in longitudinal registration with said one section, a sample conveyor mounted to said housing and comprising a plurality of means for holding samples, means for indexing said sample conveyor, said sample conveyor being mounted such that one position to which said means for holding samples are individually indexed is at said aspiration station, and control means for synchronizing indexing of said reaction conveyor and said sample conveyor.

7. The improvement of claim 6 wherein said sample conveyor is formed with parallel, longitudinally extending forward and return paths and is transversely displaced from said reaction conveyor.

8. The improvement according to claim 6 wherein said means for holding samples comprise vertically extending means for receiving tubes for containing samples.

9. The improvement of claim 8 wherein each of said means for holding samples has bosses extending from its periphery, said bosses being oppositely disposed and vertically displaced from each other, and wherein each of said means for holding samples are substantially identically formed, whereby said means for holding samples fit together to form an endless loop, and means linking adjacent means for holding sample at said bosses, whereby said sample conveyor is formed without a chain.

10. The improvement according to claim 6 wherein said means for indexing comprises sprocket means positioned in said sample conveyor at a contour linking said forward and return paths, said sprocket means having teeth formed for mating with said means for holding samples, and a motor mechanically coupled to said sprocket means and electrically coupled to said control means.

11. The improvement according to claim 10 wherein said sprocket means further comprises a set of teeth, each having an aperture therein, and photosensor means having a light path positioned to be broken by rotation of a tooth and reestablished through one of said apertures for indicating indexing of the sample conveyor.

12. The improvement according to claim 11 including means for adjusting the relative position of said photosensor means and said sprocket means, whereby a reference angular position of said sprocket means may be established.

13. The improvement according to claim 8 wherein each of said means for holding samples is formed with a hole in registration with an opening in which said tubes are inserted, and wherein means are provided at said aspiration station for periodically directing driving means through said hole, whereby relative motion is provided between each of said tubes and means for aspiration of samples.

14. The improvement of claim 7 wherein bar code labels are provided carried by each of said means for holding samples and wherein bar code reading means are mounted to said housing longitudinally displaced from said aspiration station ahead thereof with respect to the forward path of said sample conveyor.

15. The improvement of claim 14 further comprising guard means mounted for preventing removal of samples from said sample conveyor between said bar code reading means and said aspiration station.

16. The improvement according to claim 6 wherein said sample conveyor is mounted to maintain a sample at said aspiration station in vertical registration with the said one row of said reaction conveyor.

17. The improvement according to claim 6 wherein said means for holding samples comprises a vertically extending sample holder, a blood collection tube received in said sample holder and a sample cup received in said blood collection tube.

18. The improvement according to claim 10 including further sprocket means at an opposite contour of said sample conveyor positioned such that said sample conveyor is supported by both of said sprocket means.