Bovine teat dip

• US 4,049,830 A
• Filed: 11/06/1975
• Issued: 09/20/1977
• Est. Priority Date: 11/13/1974
• Status: Expired due to Term

• Current Assignee: Milmark Research Incorporated
• Original Assignee: Milmark Research Incorporated
• Inventors: Pugliese, Peter T.
• Primary Examiner(s): Schenkman, Leonard
• Application Number:
  US05/629,222
• Time in Patent Office: 684 Days
• Field of Search: 424/343
• US Class Current: 514/727
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 35/08 at least one of the bonds to hetero atoms is to nitrogen
• CPC Class Codes: A61K 9/0041 Mammary glands, e.g. breasts, udder; Intramammary administration

Abstract

A bovine teat dip effective against both gram-positive and gram-negative bacteria, and containing lipids capable of reestablishing the natural lipid barrier or of forming a protective lipid barrier to foreign matter in the treated zone so as to minimize disruption of the natural defense mechanisms against infection or irritation.

Claims

1. A bovine teat dip free of inorganic salts and having a pH of between 5.0 and 5.8, a viscosity of from 4 to 10 centipoise at 37°

C. and comprising an oil-in-water emulsion of the following ingredients expressed in parts by weight;

space="preserve" listing-type="tabular">______________________________________ polyethoxycetyl ether 0.5% 75 mole polyoxyethylene ether of whole lanolin 4.6% lauryl (poly-1-oxapropene) oxaethane carboxylic acid 1.0% propylene glycol 8.0% 2-bromo-2-nitropropan-1,3 diol 0.2% organic base as necessary to adjust pH to 5.0 to 5.8 water as necessary to bring total volume to 100% ______________________________________

2. A composition according to claim 1 which also includes a FD&

C color.

3. A composition according to claim 1 wherein the organic base is triethanolamine.

4. A method of making the composition of claim 1 which comprises combining the ingredients other than the 2-bromo-2-nitropropan-1,3 diol and water;

heating the so combined ingredients to 65°

C. to form an oil phase;

heating the requisite amount of water to 65°

C. in a separate vessel;

adding the oil phase slowly to the hot water with stirring;

adding organic base slowly and without back titrating until pH is a 5.2 to 5.5;

cooling to below 40°

C.; and

adding the 2-bromo-2-nitropropan-1,3 diol.

5. The method of controlling mastitis in dairy cattle which comprises immersing the cow'"'"'s teats in a dip according to claim 1 coating the teat with the emulsion;

forcing some emulsion into the teat orifice and into the lower portions of the streak canal by hydrostatic pressure, draining the excess emulsion from the teat without washing so as to form a protective lipid barrier, and permitting a small quantity of the emulsion to collect at and when dry to seal the teat orifice with a soft, tacky film or beadlet of water soluble lipid that maintains its tackiness for at least 12 to 24 hours but which can be removed by washing with water before the next milking.