Indole-2-carbaldehyde compounds and blood sugar reducing compositions
First Claim
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1. Indole-2-carbaldehyde compound of the formula:
- ##STR5## wherein R1 is lower alkyl of up to 5 carbon atoms andR2 is hydrogen, halogen or lower alkyl or alkoxy with the proviso that when R2 is ethyl, R1 may be hydrogenand the physiologically compatible aldehyde derivatives thereof.
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Abstract
New indole-2-carbaldehyde compounds of the formula ##STR1## wherein R1 is lower alkyl
R2 is hydrogen, halogen, or lower alkyl or alkoxy,
With the proviso that when R2 is halogen or ethyl,
R1 can also be hydrogen
And the physiologically compatible derivatives thereof, are outstandingly effective in lowering excessive blood sugar in mammals.
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Citations
15 Claims
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1. Indole-2-carbaldehyde compound of the formula:
- ##STR5## wherein R1 is lower alkyl of up to 5 carbon atoms and
R2 is hydrogen, halogen or lower alkyl or alkoxy with the proviso that when R2 is ethyl, R1 may be hydrogen and the physiologically compatible aldehyde derivatives thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- ##STR5## wherein R1 is lower alkyl of up to 5 carbon atoms and
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12. Method of depressing blood sugar in the subject which method comprises administering to such subject an effective amount of indole-2-carbaldehyde compound of the formula:
- ##STR6## wherein R1 is lower alkyl or hydrogen and
R2 is hydrogen, halogen or lower alkyl or alkoxy with the proviso that when R2 is other than halogen or ethyl, R1 is alkyl, and the physiologically compatible aldehyde derivatives thereof. - View Dependent Claims (13, 14, 15)
- ##STR6## wherein R1 is lower alkyl or hydrogen and
Specification