Disposable chemical indicators

• US 4,059,407 A
• Filed: 01/12/1977
• Issued: 11/22/1977
• Est. Priority Date: 04/14/1976
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Hochstrasser, Harry T.
• Primary Examiner(s): Serwin, R.E.
• Application Number:
  US05/758,646
• Time in Patent Office: 314 Days
• Field of Search: 23/230 B, 23/253 TP, 195/103.5 R, 195/103.5 C, 195/127, 116/114 AM
• US Class Current: 422/424
• CPC Class Codes: G01N 33/528 Atypical element structures, e.g. gloves, rods, tampons, toilet paper
• CPC Class Codes: Y10S 435/97 Test strip or test slide
• CPC Class Codes: Y10T 436/146666 Bile pigment
• CPC Class Codes: Y10T 436/148888 Uric acid

Abstract

A disposable indicator is disclosed which is useful for the measurement of ketones, proteins including albumin and uric acid in biological fluids. The instrument registers the concentration of substance in a given biological fluid with indicia which are directly readable in a convenient notation system (e.g., digital or other symbolic notation). The indicator comprises an improvement over prior art disposable devices which require a comparison of the viewable indication with a color intensity scale to translate the indicia registered to meaningful numerical values or other symbolic notations. The indicator permits the use of chemical reagent concentrations which are at least an order of magnitude greater than those used in prior art, thereby improving stability and drastically lowering the magnitude of interferences.

Claims

1. An indicator for the measurement of ketones dissolved in biological fluids, which comprises;

a support member; and

a plurality of indicating reagents for said ketones, each of which is located in a separate zone of said member and at least two of which indicate the presence of a different concentration of said ketones in solution.

2. The indicator of claim 1 wherein said support member is hydrophobic and said zones are formed of bibulous material.

3. The indicator of claim 1 wherein said reagents are disposed upon said support member in the shape of numerals corresponding to indicia for the level of substance for which they indicate.

4. An indicator for the measurement of albumin dissolved in biological fluids, which comprises:

a support member; and

a plurality of indicating reagents for said albumin, each of which is located in a separate zone of said member and at least two of which indicate the presence of a different concentration of said albumin in solution.

5. The indicator of claim 4 wherein said support member is hydrophobic and said zones are formed of bibulous material.

6. An indicator for the measurement of proteins dissolved in biological fluids, which comprises:

a support member; and

a plurality of indicating reagents for said protein, each of which is located in a separate zone of said member and at least two of which indicate the presence of a different concentration of said protein in solution.

7. The indicator of claim 6 wherein said support member is hydrophobic and said zones are formed of bibulous material.

8. An indicator for the measurement of uric acid dissolved in biological fluids, which comprises;

a support member; and

a plurality of indicating reagents for said uric acid, each of which is located in a separate zone of said member and at least two of which indicate the presence of a difference concentration of said uric acid in solution.

9. The indicator of claim 8 wherein said support member is hydrophobic and said zones are formed of bibulous material.