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Apparatus and method for selectively separating amino acids and defined proteins in blood

  • US 4,061,141 A
  • Filed: 02/04/1972
  • Issued: 12/06/1977
  • Est. Priority Date: 03/21/1969
  • Status: Expired due to Term
First Claim
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1. An apparatus for selectively separating by enzymatic degradation amino acids and defined proteins from blood for therapeutic purposes, comprising walls forming a chamber, means positioned within said chamber forming at least one laterally closed and impervious passage therethrough, an inlet to said flow passage, an outlet from said flow passage a first tube for connecting said inlet to a human artery, a second tube for connecting said outlet to a human vein so that a closed system is provided for withdrawing blood from an artery, passing it through the flow passage in said chamber and returning it to a vein, a carrier material disposed within said flow passage for direct contact with the blood flowing therethrough and an enzyme suitable for separating one of an amino acid or a defined protein from blood fixed to said carrier material in an insolubilized manner for forming an active substance which effects a selective separation of at least one of the particular substances from the blood.

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