Chromatographic septum having polyimide coating

• US 4,066,183 A
• Filed: 02/24/1977
• Issued: 01/03/1978
• Est. Priority Date: 02/24/1977
• Status: Expired due to Term

• Current Assignee: Chromatography Research Supplies, Inc. (Trajan Group Holdings Ltd.)
• Original Assignee: L
• Inventors: Armstrong, Nelson W.
• Primary Examiner(s): Cannon, J.C.
• Application Number:
  US05/771,689
• Time in Patent Office: 313 Days
• Field of Search: 428/421, 428/422, 428/474, 428/64, 128/DIG. 14, 215/DIG. 2, 215/DIG. 3, 215/DIG. 4, 215/247, 427/407
• US Class Current: 215/247
• CPC Class Codes: B01D 15/08 Selective adsorption, e.g. chromatography
• CPC Class Codes: G01N 30/18 using a septum or microsyringe
• CPC Class Codes: Y10S 128/14 Polytetrafluoroethylene, i.e. PTFE
• CPC Class Codes: Y10S 138/03 Polytetrafluoroethylene, i.e. PTFE
• CPC Class Codes: Y10S 138/07 Resins
• CPC Class Codes: Y10S 215/02 Coatings and laminations for making of bottle caps
• CPC Class Codes: Y10S 215/03 Medical
• CPC Class Codes: Y10S 215/04 Capping materials
• CPC Class Codes: Y10T 428/214 End closure
• CPC Class Codes: Y10T 428/215 Seal, gasket, or packing
• CPC Class Codes: Y10T 428/31544 Addition polymer is perhalogenated
• CPC Class Codes: Y10T 428/31721 Of polyimide

Abstract

Improved septa for chromatographic apparatus and procedures comprise disc or cylindrical bodies of silicone rubber with a coating of polyimide which may in turn be covered by a coating of Teflon.

Claims

1. In a chromatographic septum comprising a body of hypodermic needle penetrable self-healing rubber adapted to serve as a closure for a container or chromatographic system, the improvement which comprises covering the surface of the septum that is to be exposed to the interior of the container or system with a coating of polyimide polymer.

2. The septum of claim 1 wherein the septum is disc-shaped and at least one flat surface thereof is coated with the polyimide polymer.

3. The septum of claim 1 wherein the coating is itself covered by a coating of tetrafluoroethylene.

4. The septum of claim 1 wherein the septum is cylinder-shaped and the cylindrical sides as well as at least one end of the septum body is coated by the polyimide polymer.