Control apparatus for the automatic treatment of diabetes

• US 4,073,292 A
• Filed: 10/29/1976
• Issued: 02/14/1978
• Est. Priority Date: 10/29/1976
• Status: Expired due to Term

• Current Assignee: William Edelman
• Original Assignee: William Edelman
• Inventors: Edelman, William
• Primary Examiner(s): Padgett, Benjamin R.
• Assistant Examiner(s): Barr, Josephine Lloyd
• Application Number:
  US05/736,996
• Time in Patent Office: 473 Days
• Field of Search: 128/2 R, 128/2 L, 128/214 E, 128/214 B, 128/DIG. 13, 356/39, 356/41, 356/42
• US Class Current: 604/66
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/201 Assessing renal or kidney functions
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: Y10S 128/13 Infusion monitoring

Abstract

The control apparatus of the invention comprises a feedback system to maintain the level of glucose in a diabetic within predetermined limits. Surgically implanted in the body are a means for sensing glucose levels and a means for dispensing insulin in an amount determined by the sensing mechanism. The sensing mechanism employs a chemical solution, which, like the insulin, is stored within a reservoir forming part of the surgical implant. Means are additionally provided to couple these reservoirs to the surface of the skin so as to permit their rechargings at regular time intervals. Integrated circuit technology is employed to translate an indication of an unacceptable glucose level into an automatic injection of insulin, with the electronics being of the type capable of being powered by batteries of the kind employed in pacemaker technology.

Claims

1. Control apparatus for the automatic treatment of diabetes, comprising:

first means for admixing a urine sample from a living body with a chemical solution, a characteristic of which with respect to light varies as a function of the molar concentration of glucose complexes present in said sample;

second means providing said chemical solution;

third means providing a source of light;

fourth means exposed to said source of light via the admixture of said first means and responsive to the light impinging thereon for generating a control signal representative of the molar concentration of said glucose complexes present;

fifth means providing a source of modified insulin of increased pH; and

sixth means responsive to said control signal for automatically injecting a predetermined amount of said modified insulin into an artery of the body to maintain the level of glucose complexes within the blood within prescribed limits;

with said first, second, third, fourth, fifth and sixth means, being adapted to be surgically implanted within the body and with said second and fifth means being replenishable with chemical solution and insulin, respectively, without the need for additional surgical procedures.

2. The apparatus of claim 1 wherein said second means provides a chemical solution whose transparency to light varies inversely with the molar concentration of glucose complexes with which it may be admixed, and wherein said fourth means responds to the amount of light impinging thereon.

3. The apparatus of claim 1 wherein said first means includes seventh means for filtering material from a urinary fluid larger in size than said glucose complexes in providing said urine sample for admixture.

4. The apparatus of claim 1 wherein said sixth means automatically injects a predetermined amount of said modified insulin into the aorta of the body.

5. The apparatus of claim 1 wherein each of said second and fifth means include seventh means for storing a given amount of chemical solution and insulin, respectively, and eighth means coupling said storage means to the skin surface of the body for recharging said storage means by fluid injections administered thereat.

6. The apparatus of claim 1 wherein said first means is activated to provide said admixture at the time of body urination.

7. The apparatus of claim 1 wherein said sixth means is adjusted to prescribe the predetermined amounts of modified insulin to be injected in response to said control signal prior to its being surgically implanted into the body and in accordance with the particular needs of the individual into whose body the implantation is to proceed.

8. The apparatus of claim 2 wherein said third means includes a lightemitting diode and said fourth means includes a photocell.