High surface area permeable material

• US 4,075,092 A
• Filed: 08/10/1976
• Issued: 02/21/1978
• Est. Priority Date: 08/10/1976
• Status: Expired due to Term

• Current Assignee: Research Corporation
• Original Assignee: Research Corporation
• Inventors: Hanusiak, William M., White, Eugene W., White, Rodney A.
• Primary Examiner(s): Spear, Jr., Frank A.
• Assistant Examiner(s): Cross, E. Rollins
• Application Number:
  US05/713,258
• Time in Patent Office: 560 Days
• Field of Search: 210/22, 210/321 B, 210/500 M, 264/321, 264/44, 264/317 X, 264/DIG. 48, 423/308, 128/92 C, 260/2.5 R, 23/258.5
• US Class Current: 210/646
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/30 Joints
• CPC Class Codes: A61F 2002/30224 cylindrical
• CPC Class Codes: A61F 2002/30261 parallelepipedal
• CPC Class Codes: A61F 2002/30785 parallel
• CPC Class Codes: A61F 2002/30789 perpendicular with respect to each other
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0082 parallelepipedal
• CPC Class Codes: A61F 2310/00341 Coral, e.g. aragonite, porite
• CPC Class Codes: A61L 2300/214 Amino acids
• CPC Class Codes: A61L 2300/256 Antibodies, e.g. immunoglobulins, vaccines
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/406 Antibiotics
• CPC Class Codes: A61L 2300/43 Hormones, e.g. dexamethasone
• CPC Class Codes: A61L 27/36 containing ingredients of undetermined constitution or reaction products thereof , e.g. transplant tissue, natural bone, extracellular matrix isolated natural compounds, e.g. collagen A61L27/24
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: B01D 63/066 with a porous block having membrane coated passages
• CPC Class Codes: B01D 69/10 Supported membranes; Membrane supports
• CPC Class Codes: B01D 69/106 Membranes in the pores of a support, e.g. polymerized in the pores or voids
• CPC Class Codes: B01J 19/0053 Details of the reactor
• CPC Class Codes: B01J 19/0073 : Sealings sealings for pressure vessels per se F16J15/00
• CPC Class Codes: B01J 2219/00164 : controlling the flow
• CPC Class Codes: C08J 9/26 : by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
• CPC Class Codes: Y02P 20/141 : Feedstock

Abstract

Three-dimensional structures providing a plurality of separate interpenetrating, three-dimensional domains or channels or flowpaths, each of said domains or channels or flowpaths being a closed system of connected porosity or permeability and each of said domains or channels or flowpaths being interpenetrating within said structure, have been prepared. These structures are prepared from porous permeable precursor materials having a single three-dimensional domain or channel or flowpath as described above. Suitable precursor materials are provided by the abundant porous carbonate skeletal material of marine life, e.g. the coral Porites skeletal aragonite. For example, by coating the surfaces of such materials with a liquid material capable of being cured or set to a solid, followed by curing or setting and dissolution, e.g. chemical etching, of the coated skeletal material, there is produced a three-dimensional structure in accordance with this invention possessing two separate interpenetrating, three-dimensional domains or channels or flowpaths defined by the residual cured or set coating material. The resulting structure of this invention can be adapted such that a fluid can be applied to one side or face of the structure to flow into and out of such structure via only one of said channels or flowpaths and when so adapted can be employed in apparatus for the treatment or handling of one or more of the fluid streams flowing there-through.

Claims

1. An integral three-dimensional structure providing a plurality of separate interpenetrating, three-dimensional domains or channels, each of said domains or channels being a closed system of connected porosity or permeability with multiple interconnections only with respect to its respective domain or channel, each of said domains or channels being interpenetrating within said structure.

2. A structure in accordance with claim 1 wherein said integral structure is made of the same material.

3. A structure in accordance with claim 1 wherein each of said domains or channels is provided with outlets on the surface of said structure.

4. A structure in accordance with claim 1 wherein at least one of said domains or channels or flowpaths is provided with outlets on the surface of said structure.

5. A structure in accordance with claim 1 wherein said structure is made of different materials.

6. A structure in accordance with claim 1 wherein the walls of at least one of the separate interpenetrating, three-dimensional domains or channels or wherein at least one of said domains or channels is defined or made up of material which is selectively permeable.

7. A structure in accordance with claim 1 wherein there are provided two separate interpenetrating, three-dimensional domains or channels.

8. A structure in accordance with claim 1 wherein there are provided three separate interpenetrating, three-dimensional domains or channels.

9. A structure in accordance with claim 1 wherein fluid supply means are provided on a portion of the outside surface of said structure for the supply of fluid to only one of said domains or channels.

10. A structure in accordance with claim 1 wherein separate fluid supply means are provided on a portion of the outside surface of said structure for the supply of fluid to each of said domains or channels.

11. A structure in accordance with claim 1 wherein said structure is substantially tubular in shape.

12. A structure in accordance with claim 1 wherein said structure is substantially cylindrical in shape.

13. A structure in accordance with claim 1 wherein said structure is a prism.

14. A structure in accordance with claim 13 wherein said prism is a quadrangular prism.

15. A structure in accordance with claim 13 wherein said prism is a pentagonal prism.

16. A structure in accordance with claim 1 wherein the walls defining at least one of the separate interpenetrating, three-dimensional domains or channels or wherein at least one of said domains or channels is defined or made up of a material which comprises dispersed or admixed therein a reagent capable of slow release from said walls of said material.

17. A structure in accordance with claim 1 wherein at least one of said domains or channels is provided with separate fluid supply and exit means on the surfaces of said structure such that fluid supplied via said separate fluid supply means exits from said structure only via said fluid exit means.

18. A structure in accordance with claim 7 wherein each of said two separate interpenetrating, three-dimensional domains or channels is provided with separate fluid supply and exit means such that fluid supplied to each of said fluid supply means exits from said structure only from its corresponding fluid exit means.

19. A structure in accordance with claim 8 wherein each of said three separate interpenetrating, three-dimensional domains or channels is provided with separate fluid supply and exit means such that fluid supplied to each of said supply means exits from said structure only from its corresponding fluid exit means.

20. A structure in accordance with claim 1 wherein each of the domains or channels making up said plurality of separate interpenetrating, three-dimensional channels or flowpaths of said structure is provided with separate fluid supply and corresponding separate exit means such that fluid supplied to each of said supply means exits from said structure only from its corresponding fluid exit means.

21. A method of transferring or transporting a component of one flowing fluid stream to another flowing fluid stream without physically intermingling or mixing said streams which comprises flowing said one fluid stream containing said component through a first separate interpenetrating, three-dimensional channel or flowpath provided within a structure having an inlet and outlet only for said one fluid stream, flowing said other fluid stream through a second separate interpenetrating, three-dimensional channel or flowpath also provided within said structure and having an inlet and outlet only for said other fluid stream, the walls of said first channel or flowpath being defined by or made up of a material which is selectively permeable for said component such that as the first stream containing said component flows through said first channel or flowpath said component permeates or moves through said selectively permeable material making up or defining the walls of said first channel or flowpath into said other fluid flowing through said other channel or flowpath.

22. A method in accordance with claim 21 wherein said one fluid stream is a human body fluid.

23. A method in accordance with claim 22 wherein said human body fluid is arterial blood or venous blood.

24. A method in accordance with claim 21 wherein said other fluid stream is a human body fluid.

25. A method is accordance with claim 24 wherein said human body fluid is arterial blood or venous blood.

26. A method in accordance with claim 21 wherein said first fluid stream is an oxygen-containing stream, said oxygen being present therein as dissolved oxygen or gaseous oxygen, and wherein said other fluid stream is a human blood stream, said selectively permeable material making up the walls of said first channel or flowpath being permeable to oxygen.

27. A method in accordance with claim 21 wherein said component in said first fluid stream is a bio-affecting component and wherein the other fluid stream is a human blood stream.

28. A method in accordance with claim 27 wherein said bio-affecting component comprises one or more amino acids suitable for hyperalimentation.

29. A method in accordance with claim 27 wherein said bio-affecting component is a human hormone.

30. A method in accordance with claim 27 wherein said bio-affecting component is an antibiotic or antibacterial or antiviral material.