Apparatus and method for measuring the time taken for a change in viscosity to occur

• US 4,081,242 A
• Filed: 07/12/1976
• Issued: 03/28/1978
• Est. Priority Date: 07/16/1975
• Status: Expired due to Term

• Current Assignee: Antoine Girolami
• Original Assignee: Antoine Girolami
• Inventors: Girolami, Antoine
• Primary Examiner(s): Serwin, R.E.
• Application Number:
  US05/704,650
• Time in Patent Office: 624 Days
• Field of Search: 23/259, 23/253 R, 23/230 B, 23/230 R, 73/64.1, 73/57, 73/54
• US Class Current: 73/54.01
• CPC Class Codes: G01N 33/4905 Determining clotting time of blood by chemical methods G01N33/86, C12Q1/56

Abstract

An apparatus for measuring the time taken for a change to occur in the physical state of a material or medium, such as the time of appearance of a clot in a blood sample, includes a jar whose bottom may serve as a circular track for a ball, a ball able to roll around the track, a support for the jar maintaining the bottom of the jar and track in a plane inclined in relation to the horizontal plane, a means for rotating the support and jar whereby the ball remains at the lowest point of the track when the material is in the liquid state but is carried around the track by the more viscous material when that has changed its state, and a means of detecting the movement of the ball.

Claims

1. An apparatus for use in a method of detecting change of viscosity to occur in a medium, comprising:

(i) a receptacle to contain an amount of the medium, said receptacle including a planar base and a bounding wall upstanding from said base

(ii) a structure, and means mounting said receptacle on said structure for rotation of said receptacle with respect to said structure about an axis of rotation normal to the plane of said base, said structure and mounting means being such that said planar base lies at an inclination to the horizontal,

(iii) drive means on said structure coupled to said receptacle for rotating said receptacle with respect to said structure,

(iv) a ball of greater density than said medium positioned in said receptacle and supported by said planar base and said bounding wall for rolling along said base and wall as the receptacle is rotated.

2. An apparatus, as claimed in claim 1, wherein said receptacle is a cylindrical jar having said planar base and upstanding wall.

3. An apparatus, as claimed in claim 2, wherein said means mounting said receptacle on said structure include a cylindrical support receiving said cylindrical jar.

4. An apparatus, as claimed in claim 1, further comprising means for producing a beam of radiation for passing through said receptacle, and means for detecting said beam of radiation after passing through said receptacle, said receptacle being permeable to said radiation, and said ball being impermeable to said radiation.

5. An apparatus, as claimed in claim 1, wherein said means mounting said receptacle on said structure include a support receiving said receptacle, said support having opposed apertures aligned with the position occupied by the ball in the receptacle when supported by the base and bounding wall of the receptacle, and further comprising means for producing a beam of radiation for passing through said receptacle and the apertures of said support, said receptacle being permeable to said radiation, said support and said ball being impermeable to said radiation, and means for detecting said beam of radiation after passing through said receptacle and the apertures of said support.

6. A method, of detecting a change of viscosity in a medium, which comprises the steps of:

(i) placing a quantity of medium in a receptacle having a planar base and a bounding wall upstanding from said base

(ii) placing a ball in said medium in said receptacle

(iii) rotating said receptacle, containing said medium and said ball, about an axis normal to the plane of said base, said axis being at an inclination to the horizontal, and

(iv) detecting any change occurring, in either direction, between a first state of viscosity of the medium in which the ball remains substantially in the same position as it is supported by and rolls along said base and bounding wall, and a second state of viscosity of the medium in which the ball is carried by the medium about the axis of rotation of the receptacle.