Chromatographic column fittings

• US 4,083,702 A
• Filed: 07/19/1976
• Issued: 04/11/1978
• Est. Priority Date: 07/19/1976
• Status: Expired due to Term

• Current Assignee: Perkinelmer Incorporated
• Original Assignee: Perkinelmer Incorporated
• Inventors: Wilson, Francis Paul, Hartigan, Martin Joseph
• Primary Examiner(s): Adee, John
• Application Number:
  US05/706,897
• Time in Patent Office: 631 Days
• Field of Search: 55/67, 55/197, 55/386, 285/156, 285/176, 285/177, 285/239, 285/242, 285/245
• US Class Current: 96/106
• CPC Class Codes: G01N 30/6039 in series

Abstract

A chromatographic column fitting for connecting the column to a connecting tube, which includes a union having an axial through-bore that includes at both ends thereof: a first portion, a second inwardly tapered portion, and a third cylindrical portion connecting the second portions of both ends; one end of the connecting tube being receivable in one end of the union and one end of the column tube being receivable in the other end of the union so that the end of the two tubes engage in butt-to-butt relationship; and ferrules wedged between the outside surfaces of the tubes and their adjacent second portions of the union, respectively; and in another form thereof the invention provides an outlet column fitting which includes a T-shaped union having an inlet at one end and an outlet at the other end and having an axial through-bore, which includes sequentially from the inlet to the outlet, a first inwardly tapered portion, a second cylindrical portion, a third manifold portion, the union having a side inlet opening into the manifold and the outlet end of the column tube being receivable in the inlet end of the union and extending through the first and second portions and into the manifold portion to a point toward the outlet end thereof so that make-up gas sweeps the outlet of the column tube, and a second connecting tube being connected to the outlet of the union.

Claims

1. In a chromatograph having a chromatographic column tube and a connection tube, a fitting for interconnecting said tubes comprising:

a union member having an axial through-bore which includes at both ends thereof;

a first portion,

a second inwardly tapered portion connected to the first portion, and

a third cylindrical portion connecting the second portion of one end of the union member with the second portion of the other end of the union member;

one end of said connecting tube being receivable in one end of said union member and one end of said column tube being receivable in the other end of said union member, said one end of said connecting tube and said one end of said column tube being engageable in butt-to-butt relationship within said union member,

means for wedging ferrule means between the outside surface of said connecting tube and the adjacent second portion of said union member to retain said connecting tube in said union member, and means for wedging second ferrule means between the outside surface of said column tube and the adjacent second portion of said union member to retain said column tube within said union member, the adjacent ends of the two ferrule means being disposed in essentially ferrule-to-ferrule orientation with respect to each other within said union member, and the two ferrule means extending substantially to the ends of the tubes respectively.

2. A chromatographic column fitting according to claim 1 wherein said one end of said column tube is the inlet end of said chromatographic column.

3. A chromatographic column fitting according to claim 1 wherein said first portion of said axial through-bore is cylindrical and part thereof has internal threads for receiving internal tightening nuts for wedging said ferrule means, respectively.

4. A chromatographic column fitting according to claim 1 wherein said first and second portions of said axial through-bore of said union member are connected by a chamfer.

5. A chromatographic column fitting according to claim 1 wherein said ferrule means are tapered polymeric ferrules.

6. In a chromatograph having a chromatographic column tube and a connecting tube, a fitting for interconnecting said tubes comprising:

a union member having an axial through-bore which includes at both ends thereof;

a first portion,

a second inwardly tapered portion connected to the first portion, and

a third cylindrical portion connecting the second portion of one end of the union member with the second portion of the other end of the union member;

one end of said connecting tube being receivable in one end of said union member and one end of said column tube being receivable in the other end of said union member, said one end of said connecting tube and said one end of said column tube being engageable in butt-to-butt relationship within said union member, said ends of said tubes engaging each other adjacent the intersection of the second inwardly tapered portion and the third cylindrical portion, at the end of the union member receiving the connecting tube,

means for wedging ferrule means between the outside surface of said connecting tube and the adjacent second portion of said union member to retain said connecting tube in said union member, and means for wedging second ferrule means being the outside surface of said column tube and the adjacent second portion of said union member to retain said column tube within said union member.

7. A chromatographic column fitting according to claim 6 wherein the location of said ferrule-to-ferrule orientation of the two ferrule means and the location of the engagement of the ends of the two tubes are adjacent each other.

8. A chromatographic column fitting according to claim 7 wherein said column tube is a glass capillary tube and said connecting tube is a glass lined stainless steel tube.

9. A chromatographic column fitting according to claim 8 wherein the outside diameter of said glass lined stainless steel tube is substantially greater than the outside diameter of said glass capillary tube.

10. In a chromatograph having a chromatographic column tube and a connecting tube, a fitting for interconnecting said tubes comprising:

a union member having an axial through-bore which includes at both ends thereof;

a first portion,

a second inwardly tapered portion connected to the first portion, and

a third cylindrical portion connecting the second portion of one end of the union member with the second portion of the other end of the union member;

one end of said connecting tube being receivable in one end of said union member and one end of said column tube being receivable in the other end of said union member, said one end of said connecting tube and said one end of said column tube being engageable in butt-to-butt relationship within said union member,

means for wedging ferrule means between the outside surface of said connecting tube and the adjacent second portion of said union member to retain said connecting tube in said union member, and means for wedging second ferrule means between the outside surface of said column tube and the adjacent second portion of said union member to retain said column tube within said union member,

said one end of said column tube being the inlet end of said chromatographic column, and the apparatus further including a second connecting tube, and a second fitting which comprises;

a T-shaped union member having an inlet at one end and an outlet at the other end thereof, said T-shaped union member having an axial through-bore which includes sequentially from the inlet to the outlet;

a first inwardly tapered portion,

a second cylindrical portion connected to the first portion, a third elongated cylindrical manifold portion connected to the second portion, and

a fourth outwardly tapered portion;

said T-shaped union member having side inlet means opening into said manifold portion for receiving make-up gas;

the outlet end of said column tube being receivable in the inlet end of said union member and extending through said first and second portions and into said manifold portion to a point towards the outlet end thereof with respect to the opening of said side inlet means so that make-up gas sweeps the outlet end of the column tube; and

means for connecting the second connecting tube to the outlet of said T-shaped union member.

11. Apparatus according to claim 10 wherein said column tube is a glass capillary tube and the first mentioned connecting tube is a glass lined stainless steel tube.

12. Apparatus according to claim 11 wherein the outside diameter of said glass lined stainless steel tube is substantially greater than the outside diameter of said glass capillary tube.

13. In a chromatograph having a chromatographic column tube and a connecting tube, a fitting for interconnecting the outlet of said column tube with one end of said connecting tube comprising:

a T-shaped union member having an inlet at one end and an outlet at the other end thereof, said union member having an axial through-bore which includes sequentially from the inlet to the outlet;

a first inwardly tapered portion,

a second cylindrical portion connected to the first portion

a third elongated cylindrical manifold portion connected to the second portion, and

a fourth outwardly tapered portion;

said union member having side inlet means opening into said manifold portion for receiving make-up gas;

the outlet end of said column tube being receivable in the inlet end of said union member and extending through said first and second portions and into said manifold portion to a point towards the outlet end thereof with respect to the opening of said side inlet means so that make-up gas sweeps the outlet end of the column tube; and

means for connecting the connecting tube to the outlet of said union member.

14. A chromatographic column fitting according to claim 13 wherein said column tube is a glass capillary tube.

15. A chromatographic column fitting according to claim 13 wherein said second cylindrical portion has a diameter substantially equal to the outside diameter of the column tube for receiving the column tube with an interference fit therebetween.

16. In a chromatograph having a chromatographic glass capillary column tube, a glass lined connecting tube and a fitting for interconnecting said tubes, said fitting comprising a union member having an axial through-bore which includes at both ends thereof;

a first portion, a second inwardly tapered portion connected to the first portion, and a third cylindrical portion connecting the second portion of one end of the union member with the second portion of the other end of the union member;

a method of assembling said fitting comprising the steps of;

inserting into one end of said union member one end of the glass lined tube together with an associated tapered polymeric ferrule until the ferrule engages the adjacent second inwardly tapered portion, and inserting into the other end of said union member one end of the glass capillary tube together with an associated tapered polymeric ferrule until the ferrule engages its adjacent second inwardly tapered portion; and

thence

urging the glass lined tube with its associated ferrule inwardly and compressing said ferrule until both the inner end of the glass lined tube and the inner end of the ferrule reach the intersection of the third cylindrical portion and the adjacent second tapered portion, and then urging the glass capillary tube inwardly until the end thereof engages the end of the glass lined tube in butt-to-butt relationship; and

thence

urging inwardly and compressing the ferrule associated with the glass capillary tube until the inner end of the ferrule extends substantially to the inner end of the glass capillary tube to form an essentially ferrule-to-ferrule relationship with respect to the end of the ferrule associated with the glass lined tube;

whereby

said tubes are held in position by means of the wedging effect of the ferrules between the outside surfaces of the tubes and the second inwardly tapered portions, respectively.