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Indicator for use in selection of bactericidal and bacteristatic drugs and method for producing same

  • US 4,087,332 A
  • Filed: 07/22/1977
  • Issued: 05/02/1978
  • Est. Priority Date: 05/07/1976
  • Status: Expired due to Term
First Claim
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1. An indicator for use in the selection of bactericidal and bacteristatic drugs, comprising a solid elongated carrier sheet having an upper layer with a porous front surface and a moisture-tight backing, said upper layer being made of heat or pressure sensitive material that has interconnected passages pervious to moisture and being of a material consistency that permits said passages to be closed solely by application of heat or pressure without application of any additional moisture-sealing material, a plurality of testing coatings arranged on said front surface in spaced relationship to each other, said testing coatings comprising a plurality of spaced stripes on said porous front surface and extending parallel to the longitudinal axis of said carrier sheet, one of said coating stripes consisting only of a nutrition substrate for bacteria and constituting a comparison stripe, the other coating stripes constituting a mixture of a nutrition substrate and a different bactericidal or bacteristatic drug, and a moisture barrier band consisting of said passages that have been closed between each adjacent pair of said coating stripes formed by the application of heat or pressure to the front surface of said carrier sheet, said carrier sheet comprising a continuous length of adsorbent or absorbent sheet material with said porous front surface serving as an integral mechanical carrier for said testing coatings, said carrier sheet being adapted to be separated transversely at even intervals into small transverse panels, each containing said coating stripes, the coating stripe sections on said panels, when impregnated by a testing specimen, serving as individual bacteria culture media, whereby differences in bacteria colonization between the comparison stripe and the other coating stripes may be ascertained by direct visual observation.

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