Graft forming device

• US 4,108,161 A
• Filed: 11/08/1976
• Issued: 08/22/1978
• Est. Priority Date: 10/28/1975
• Status: Expired due to Term

• Current Assignee: Ernest C. Wood, Peter B. Samuels
• Original Assignee: Ernest C. Wood, Peter B. Samuels
• Inventors: Samuels, Peter B., Wood, Ernest C.
• Primary Examiner(s): Truluck, Dalton L.
• Application Number:
  US05/739,650
• Time in Patent Office: 652 Days
• Field of Search: 128/1 R, 128/334 R, 3/1, 3/1.4, 260/363, 260/364, 260/438
• US Class Current: 600/36
• CPC Class Codes: A61F 2/062 Apparatus for the production of blood vessels made from natural tissue or with layers of living cells prostheses made from natural tissue or living cells A61L27/507
• CPC Class Codes: Y10S 623/921 Blood vessel

Abstract

A device for the preparation of a graft in which a flexible tubular porous base member is suspended within a tubular enclosure with means for sealing the enclosure and for the introduction of blood while removing air from the enclosure co-incident with the introduction of blood and in which the porous tubular base member onto which the blood is clotted in forming the graft embodies axially spaced corrugations to permit stretchability for working the graft to enhance permeation of the blood and to permit easy bending without collapse.

Claims

1. A device for use in the preparation of a graft for blood vessels comprising a hollow tubular member formed of a fluid impervious material and open at one end, a removable closure adapted to engage the open end of the tubular member in sealing relation, an elongate flexible porous base member suspended from the closure into the hollow tubular member, said porous base member being dimensioned in the crosswise direction to be less than that of the hollow tubular member to provide a spaced relation between the porous base member and the inner wall of the tubular member, said porous base member having axially spaced corrugations to enable the base member to be stretched in the axial direction and bendable in all of the directions without collapse, a passage through said removable closure for insertion of a member connecting the interior of the hollow tubular member with a source of blood, and another sealable passage communicating with the interior of the hollow tubular member for the removal of gases from within the tubular member co-incident with the introduction of blood therein.

2. A device as claimed in claim 1 in which the other sealable passage is in the form of a vent which embodies a valve member controlling the opening and closing of the vent.

3. A device as claimed in claim 1 in which the other passage is in the form of a second passage through the closure for communicating with the interior of the hollow tubular member.

4. A device as claimed in claim 1 in which the hollow tubular member is formed of a translucent plastic material.

5. A device as claimed in claim 1 in which the porous tubular base member is formed of a textile material.

6. A device as claimed in claim 1 in which the porous tubular base member is formed of a plastic material having porous walls.

7. A device as claimed in claim 1 which includes an insert within an elongate flexible porous base member dimensioned to fill the major portion of the interior thereof.

8. A device as claimed in claim 7 in which the insert is dimensioned to have a length greater than the length of the porous tubular base member when in the relaxed state thereby to maintain the tubular base member in a stretched condition.

9. A device as claimed in claim 7 in which the insert is in the form of a hollow rod.

10. A device as claimed in claim 7 in which the insert is in the form of a solid rod.