Paper booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the male

• US 4,108,729 A
• Filed: 05/16/1977
• Issued: 08/22/1978
• Est. Priority Date: 05/16/1977
• Status: Expired due to Term

• Current Assignee: US Packaging Corporation
• Original Assignee: US Packaging Corporation
• Inventors: Mennen, Frederick C.
• Primary Examiner(s): Wolk, Morris O.
• Assistant Examiner(s): Turk, Arnold
• Application Number:
  US05/797,467
• Time in Patent Office: 463 Days
• Field of Search: 23/253 TP, 195/127, 195/103.5 R, 195/103.5 M
• US Class Current: 435/287.8
• CPC Class Codes: C12Q 1/12 Nitrate to nitrite reducing bacteria
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10S 435/871 Neisseria

Abstract

A paper booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the Male comprising staggered strips, a to d, back to front of (a) a bibulous paper specimen collector, (b) a bibulous paper reagent impregnated strip, (c) a bibulous paper target strip to which is applied a drop of physiological saline in the target circle, and (d) an impervious strip of polymer-coated paper which is used to squeeze the drop of saline from strip (c) through strip (b) to permit the specimen collected on strip (a) to interact with reagent in strip (b) and create color which presumptively diagnoses Neisseria Gonorrhoeae in the male.

Claims

1. A booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the male consisting essentially of four staggered strips, (a) through (d), of bibulous iron-free absorptive material in overlying relation with (a) through (d) lying back to front in the booklet;

strip (a) being a bibulous collector strip having a target circle between its ends for collecting a sample of exudate from the meatus of a male penis in the target circle;

strip (b) overlying strip (a) being a reactor strip consisting of bibulous material impregnated with a chromogen reagent and being substantially color free;

strip (c) overlying strip (b) being a bibulous wettor strip having a wettor target circle overlying said target circle of said collector strip whereby one or two drops of physiological saline applied to the wettor target circle passes through strip (b) to carry chromogen reagent wet with said one or two drops into the target circle of said collector strip to create a color change on the back side of said strip (a) in the presence of Neisseria Gonnorrhoeae in the exudate applied to strip (a);

strip (d) overlying strip (c) consisting of polymer coated material serving to press the one or two drops of physiological saline through (c), (b) and (a);

a gradient color scale range strip located beneath strip (a) whereby subsequent to sampling and pressing, strip (a) can be lifted to achieve an open book effect to view the color change on the back of strip (a) against said gradient color scale range; and

said chromogen reagent selected from the group consisting essentially of p-amino dimethylaniline oxalate, N, N-dimethyl-p-phenylenediamine dihydrochloride, N, N-dimethyl-p-phenylenediamine oxalate, N, N-dimethyl-p-phenylenediamine monohydrochloride and N. N. N'"'"' N'"'"' tetra-methyl-p-phenylenediamine dihydrochloride.

2. A booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the male consisting essentially of four staggered strips, (a) through (d), of bibulous iron-free absorptive material in overlying relation with (a) through (d) lying back to front in the booklet;

strip (a) being a bibulous collector strip having a target circle between its ends for collecting a sample of exudate from the meatus of a male penis in the target circle;

a wrapping about strip (a) to maintain it sterile;

strip (b) overlying strip (a) being a reactor strip consisting of bibulous material impregnated with a chromogen reagent and being substantially color free;

strip (c) overlying strip (b) being a bibulous wettor strip having a wettor target circle overlying said target circle of said collector strip whereby one or two drops of physiological saline applied to the wettor target circle passes through strip (b) to carry chromogen reagent wet with said one or two drops into the target circle of said collector strip to create a color change on the back side of said strip (a) in the presence of Neisseria Gonorrhoeae in the exudate applied to strip (a);

strip (d) overlying strip (c) consisting of polymer coated material serving to press the one or two drops of physiological saline through (c), (b) and (a);

a gradient color scale range strip located beneath strip (a) whereby subsequent to sampling and pressing, strip (a) can be lifted to achieve an open book effect to view the color change on the back of strip (a) against said gradient color scale range; and

said chromogen reagent selected from the group consisting essentially of p-amino dimethylaniline oxalate, N, N-dimethyl-p-phenylenediamine dihydrochloride, N, N-dimethyl-p-phenylene-diamine oxalate, N, N-dimethyl-p-phenylenediamine monohydrochloride and N, N, N'"'"' N'"'"' tetra-methyl-p-phenylenediamine dihydrochloride.

3. A booklet as claimed in claim 2 wherein said wrapper has a tear open string for removal of the wrapping.