Polyurethane hydrogel and method for the production of the same

• US 4,118,354 A
• Filed: 08/17/1976
• Issued: 10/03/1978
• Est. Priority Date: 11/24/1972
• Status: Expired due to Term

• Current Assignee: Dai-Ichi Kogyo Seiyaku Company Limited (DKS Co., Ltd.)
• Original Assignee: Dai-Ichi Kogyo Seiyaku Company Limited (DKS Co., Ltd.)
• Inventors: Harada, Hideo, Matsushita, Nobuaki
• Primary Examiner(s): Tillman, Murray
• Assistant Examiner(s): Koeckert, A. H.
• Application Number:
  US05/715,056
• Time in Patent Office: 777 Days
• Field of Search: 260/29.2 TN, 260/77.5 AP
• US Class Current: 524/711
• CPC Class Codes: C08G 18/10 Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
• CPC Class Codes: C08G 18/302 Water
• CPC Class Codes: C08G 18/4837 and other oxyalkylene units
• CPC Class Codes: C08G 2210/00 Compositions for preparing hydrogels

Abstract

The improved polyurethane hydrogel is produced by dispersing a reaction product obtained by the reaction of a polyisocyanate having at least two isocyanate groups with a polyether. The polyether comprises a plurality of alkylene oxides, 50 to 90% by weight of which is ethylene oxide, added at random to a polyalcohol having at least two terminal hydroxyl groups in an amount of an average molecular weight within the range of 1,000 to 4,000 per said hydroxyl terminal group of said polyalcohol. The improved polyurethane hydrogel can have a greater water content and is highly stable and highly elastic.

Claims

1. A polyurethane hydrogel obtained by dispersing:

(a) a reaction product obtained by the reaction of polyisocyanate having at least two isocyanate groups with a polyether into

(b) an aqueous liquid phase;

wherein the amounts of said (a) and (b) are such that the hydrogel product has a water content of 70 to 95% by weight and wherein said polyether is produced from a plurality of alkylene oxides, 75 to 85% by weight of which is ethylene oxide, added at random to a polyalcohol having at least two terminal hydroxyl groups in an amount to produce an average molecular weight of 2000 to 3000 per said terminal hydroxyl group of said polyalcohol.

2. The polyurethane hydrogel of claim 1, wherein said polyalcohol is ethylene glycol.

3. The polyurethane hydrogel of claim 1, wherein said polyalcohol has three terminal hydroxyl groups.

4. The polyurethane hydrogel of claim 3, wherein said polyalcohol is glycerine.

5. A polyurethane hydrogel as defined in claim 1, in which said polyether comprises ethylene oxide and propylene oxide added at random to glycerine in an amount of an average molecular weight within the range of 2,000 to 3,000 per terminal hydroxyl group of said glycerine, said ethylene oxide and propylene oxide being contained in said polyether at the ratio within the range of 75:

25 to 85;

15 by weight, respectively.

6. The polyurethane hydrogel of claim 1, wherein said polyalcohol is sorbitol.

7. The polyurethane hydrogel of claim 1, wherein the polyisocyanate is reacted with the polyether in an NCO/OH ratio of at least about 3.

8. A polyurethane hydrogel as defined in claim 1, in which said aqueous liquid phase is water or an aqueous solution or dispersion.

9. A polyurethane hydrogel as defined in claim 4, in which said aqueous liquid phase is sea water.

10. The polyurethane hydrogel of claim 4, wherein the aqueous phase is a solution of a carbonate, phosphate, oxalate or phthalate.

11. A method for the production of a polyurethane hydrogel comprising dispersing:

(a) a reaction product obtained by the reaction of polyisocyanate having at least two isocyanate groups with a polyether, into

(b) an aqueous liquid phase to form a hydrogel;

wherein the amounts of said (a) and (b) are such that the hydrogel product has a water content of 70 to 95% by weight and wherein said polyether is produced from a plurality of alkylene oxides, 75 to 85% by weight of which is ethylene oxide, added at random to a polyalcohol having at least two terminal hydroxyl group in an amount to produce an average molecular weight of 2000 to 3000 per said terminal hydroxyl group of said polyalcohol.

12. The method of claim 11, wherein said polyalcohol is ethylene glycol.

13. The method of claim 11, wherein said polyalcohol has three terminal hydroxyl groups.

14. The method of claim 13, wherein said polyalcohol is glycerine.

15. A method for the production of polyurethane hydrogel as defined in claim 11, in which polyether comprises ethylene oxide and propylene oxide added at random to glycerine in an average molecular weight within the range of 2,000 to 3,000 per terminal hydroxyl group of said glycerine, said ethylene oxide and propylene oxide being contained in said polyether at the ratio within the range of 75:

25 to 85;

15 by weight, respectively.

16. The method of claim 11, wherein said polyalcohol is sorbitol.

17. The method of claim 11, wherein the polyisocyanate is reacted with the polyether in an NCO/OH ratio of at least about 3.

18. A method for the production of a polyurethane hydrogel as defined in claim 11, in which said aqueous liquid phase is water or an aqueous solution or dispersion.

19. A method for the production of polyurethane hydrogel as defined in claim 14, in which aqueous liquid phase is sea water.

20. The method of claim 14, wherein the aqueous liquid phase is a solution of a carbonate, phosphate, oxalate or phthalate.