Liquid velocity measuring system

• US 4,122,713 A
• Filed: 05/19/1977
• Issued: 10/31/1978
• Est. Priority Date: 05/19/1977
• Status: Expired due to Term

• Current Assignee: Hemadyne Corporation
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Stasz, Peter, Patten, Floyd R.
• Primary Examiner(s): Ruehl, Charles A.
• Application Number:
  US05/798,670
• Time in Patent Office: 530 Days
• Field of Search: 73/194 A, 73/67.6, 73/67.7, 73/19, 73/61 R, 128/2 V, 128/2.05 F, 128/2.05 Z, 128/214 E, 128/DIG. 13, 340/237 R
• US Class Current: 73/861.25
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/3663 Flow rate transducers; Flow integrators
• CPC Class Codes: G01F 1/663 by measuring Doppler frequency shift
• CPC Class Codes: G01N 2291/014 Resonance or resonant frequency
• CPC Class Codes: G01N 2291/02466 Biological material, e.g. blood
• CPC Class Codes: G01N 2291/02836 Flow rate, liquid level
• CPC Class Codes: G01N 29/48 by amplitude comparison
• CPC Class Codes: G01P 5/242 involving continuous, e.g. modulated or unmodulated, waves G01P5/244 takes precedence

Abstract

A liquid velocity measuring system is described utilizing ultrasonic waves to measure the velocity of a liquid and in particular, the velocity of blood as directed through a conduit external of the patient'"'"'s body. The liquid velocity measuring system comprises an ultrasonic soundwave transmitting transducer energized by a continuous wave generator, preferably at a frequency of 3.13 MHz. The transmitting transducer is disposed with respect to the conduit such that the transmitted ultrasonic waves are backscattered or reflected from ultrasonic reflection centers in the blood. This signal is received and detected by a second ultrasonic transducer. The reflected ultrasonic wave is frequency-shifted dependent upon the velocity of the liquid directed through the conduit and is detected by the second transducer to be amplified and demodulated subsequently, before being applied to a microbubble detection circuit in accordance with the teachings of this invention. In particular, the microbubble detection circuit rectifies and filters the backscattered signal before applying it to a comparator circuit. In the presence of microbubbles within the liquid, the reflected ultrasonic wave will increase in amplitude at least 15-fold over that liquid, and in particular, blood without microbubbles. The comparator is set to provide an output signal if the strength of the detected signal increases 15-fold, to provide an output signal for setting a flip-flop whose output in turn energizes an alarm indicative of the presence of microbubbles.

Claims

1. An ultrasonic wave system for measuring the characteristics of a liquid flowing through a conduit, said system comprising:

(a) first and second transducer elements operatively associated with the conduit for respectively transmitting an ultrasonic wave into the liquid flowing through the conduit and for receiving an ultrasonic wave backscattered by the liquid directed through the conduit;

(b) generator means for applying a high-frequency signal to said first transducer element causing it to emit the ultrasonic wave into the liquid;

(c) said second transducer element providing an electrical output signal of a frequency corresponding to that high frequency of said generator means, amplitude-modulated in accordance with the backscattered signal derived from the liquid, the frequency having been shifted from that high frequency of said generator means by the Doppler phenomenon, dependent upon the velocity of the liquid directed through the conduit and whose amplitude is dependent on the acoustic impedance of the liquid;

(d) first means coupled to receive the electrical output of said second transducer element for providing an amplitude demodulated output signal, bearing frequency components of the shifted frequency;

(e) second means responsive to an increase in the amplitude output of said demodulating means for providing an alarm manifestation indicating an increase in the acoustic impedance due to presence of gaseous bubbles within the liquid directed through the conduit; and

(f) third means coupled to receive the output signal of said first means and responsive to the frequency shift for providing a manifestation of the rate of the liquid flow.

2. The ultrasonic wave system as claimed in claim 1, wherein the liquid directed through the conduit is blood and said second means is responsive to a 15-fold or greater increase for providing the alarm manifestation.

3. The ultrasonic wave system as claimed in claim 1, wherein said first transducer comprises an LTZ-1 crystal material and said second transducer comprises an LTZ-5 crystal material.

4. The ultrasonic wave system as claimed in claim 1, wherein said generator means applies an electrical signal having a frequency of approximately 3.13 MHz.

5. The ultrasonic wave system as claimed in claim 1, wherein said first means comprises a radio frequency amplifier for first amplifying the output of said second transducer element, and an amplitude demodulating circuit for providing an output in accordance with the amplitude modulation of the output signal derived from said second transducer element.

6. The ultrasonic wave system as claimed in claim 1, wherein said second means comprises a comparator for making a comparison between the amplitude of the output of said first means and a reference signal.

7. The ultrasonic wave system as claimed in claim 1, wherein there is further included means responsive to the frequency shift of the output of said demodulating means for providing a first alarm manifestation indicative of a liquid flow greater than a first, predetermined rate.

8. The ultrasonic wave system as claimed in claim 1, wherein said third means includes means responsive to the frequency shift in the output of said demodulating means for providing a second alarm manifestation indicative of a rate of liquid flow through the conduit below a second predetermined level.

9. The ultrasonic wave system as claimed in claim 1, wherein the liquid flowing through the conduit is a patient'"'"'s blood, and wherein said third means comprises means responsive to the frequency shift in the output of said demodulating means for providing a first alarm manifestation indicative of a rate of blood flow through the conduit above a first level tending to rupture the patient'"'"'s artery through which the blood flows, and a second alarm manifestation indicative of a rate of blood flow through the conduit below a second level that is insufficient for the patient.

10. An ultrasonic wave system for measuring the characteristics of a liquid flowing through a conduit, said system comprising:

(a) first and second transducer elements operatively associated with the conduit for respectively transmitting an ultrasonic wave into the liquid flowing through the conduit and for receiving an ultrasonic wave backscattered by the liquid directed through the conduit;

(b) generator means for applying a high-frequency signal to said first transducer element causing it to emit the ultrasonic wave into the liquid;

(c) said second transducer element providing an electrical output signal of a frequency corresponding to that high frequency of said generator means, amplitude-modulated in accordance with the backscattered signal derived from the liquid, the frequency having been shifted from that high frequency of said generator means by the Doppler phenomenon, dependent upon the velocity of the liquid directed through the conduit and whose amplitude is dependent on the acoustic impedance of the liquid;

(d) first means coupled to receive the electrical output of said second transducer element for amplitude demodulating its output; and

(e) second means comprising a comparator for making comparison between the amplitude of the output of said first means and a reference signal for providing an alarm manifestation indicating an increase in the acoustic impedance due to presence of gaseous bubbles within the liquid directed through the conduit, and memory means coupled to the output of said comparator for providing a first output signal upon being actuated by the output of said comparator, a first alarm responsive to the first output signal to provide a visual manifestation of the presence of the gaseous bubbles within the liquid directed through the conduit, and a second alarm coupled to a second output of said memory means for providing an indication of the absence of gas bubbles within the liquid.

11. The ultrasonic wave system as claimed in claim 10, wherein said second means further comprises a first amplifier for amplifying the output of said first means, a rectifier for rectifying same and a filter, the filtered output being applied to the first input of said comparator.

12. The ultrasonic wave system as claimed in claim 11, wherein said filter is characterized by a time constant of sufficient duration to prevent the momentary presence of bubbles within the liquid from actuating said second means to provide the alarm manifestation.