Implantable dosing device

• US 4,140,122 A
• Filed: 06/02/1977
• Issued: 02/20/1979
• Est. Priority Date: 06/11/1976
• Status: Expired due to Term

• Current Assignee: Siemens AG
• Original Assignee: Siemens AG
• Inventors: Luft, Gunter, Kuhl, Dieter
• Primary Examiner(s): Sebastian, Leland A.
• Application Number:
  US05/802,963
• Time in Patent Office: 628 Days
• Field of Search: 128/130, 128/213, 128/272, 128/260, 424/19, 424/228
• US Class Current: 604/890.1
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

The invention relates to an implantable dosing device for the continuous release of medication in the human or animal body, comprising a medicine reservoir of variable volume and a propellant chamber of variable volume tensionally connected to the medicine reservoir, as well as flow-control means. According to the invention, an electro-osmotic control valve with an ion exchange diaphragm arranged between two porous electrodes is provided for the flow control in such a dosing device.

Claims

1. An implantable dosing device for the continuous release of medication in the human or animal body, comprising a medicine reservoir of variable volume, a propellant chamber of variable volume tensionally connected to said medicine reservoir, and means for controlling the flow of said medication to the body, said means comprising an electro-osmotic regulating valve comprising an ion exchange diaphragm arranged between two porous electrodes, whereby liquid is transported through the electrodes and diaphragm when current flows.

2. An implantable dosing device according to claim 1 wherein the medicine reservoir is separated from the propellant chamber by an elastic partition and the electro-osmotic regulating valve is arranged at the medicine reservoir.

3. An implantable dosing device according to claim 1 wherein a liquid chamber of variable volume is provided between the propellant chamber and the medicine reservoir, separated from both the propellant chamber and the medicine reservoir by an elastic partition and, wherein the electro-osmotic regulating valve is arranged in the liquid chamber.

4. An implantable dosing device according to claim 1 wherein the porous electrodes of said electro-osmotic regulating valve are silver/silver chloride electrodes.

5. An implantable dosing device according to claim 1 wherein a volatile liquid is provided as the propellant in the propellant chamber.

6. An implantable dosing device according to claim 5, wherein said propellant is a low hydrocarbon-halogen compound.

7. An implantable dosing device according to claim 1 wherein the propellant chamber further contains an electrolyte and two electrodes separated by a hydrophilic diaphragm for generating a gas serving as the propellant.

8. An implantable dosing device according to claim 7, wherein at least one of the electrodes in the propellant chamber is a palladium-hydrogen electrode.