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Method for producing maytansinol and its derivatives

  • US 4,151,042 A
  • Filed: 06/29/1977
  • Issued: 04/24/1979
  • Est. Priority Date: 03/31/1977
  • Status: Expired due to Term
First Claim
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1. A method for preparing maytansinol, maytanacine or maytansinol propionate which comprises cultivating a microorganism belonging to the genus Nocardia and being capable of producing maytansinol, maytanacine or maytansinol propionate in a culture medium containing assimilable carbon sources and digestible nitrogen sources until maytansinol, maytanacine or maytansinol propionate is substantially accumulated therein, and recovering the same.

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