Stopper for two-chamber mixing syringe
First Claim
1. A stopper assembly adapted for use in connecting a container with one component therein to a piston and cylinder type syringe assembly with a liquid component therein, with the components initially separated by the stopper assembly prior to permissive mixing of the components in the container upon manipulation of the stopper assembly;
- and comprising a centrally bored first stopper adapted for insertion in the container opening and receiving the syringe access fitting in the bore thereof; and
a second stopper passing into the adjacent end of the said bore for sealing the bore and the opening to the syringe fitting whereby to maintain the components separated when the container and syringe assembly are mounted to the stopper assembly;
said second stopper being releasable from its connection with the first stopper to drop into the container when the syringe piston is urged inwardly whereby to permit the component in the syringe to access to the component in the container for mixing therein.
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Accused Products
Abstract
A two-chamber syringe assembly for medicinal purposes consisting of a piston syringe having a chamber for a liquid; a container as a second chamber for a solid or another liquid; a stopper with an axial bore connecting the syringe to the vial; and a second stopper sealing the axial bore and adapted to be ejected with the liquid in the syringe into the container by inward activation of the piston of the syringe.
72 Citations
7 Claims
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1. A stopper assembly adapted for use in connecting a container with one component therein to a piston and cylinder type syringe assembly with a liquid component therein, with the components initially separated by the stopper assembly prior to permissive mixing of the components in the container upon manipulation of the stopper assembly;
- and comprising a centrally bored first stopper adapted for insertion in the container opening and receiving the syringe access fitting in the bore thereof; and
a second stopper passing into the adjacent end of the said bore for sealing the bore and the opening to the syringe fitting whereby to maintain the components separated when the container and syringe assembly are mounted to the stopper assembly;
said second stopper being releasable from its connection with the first stopper to drop into the container when the syringe piston is urged inwardly whereby to permit the component in the syringe to access to the component in the container for mixing therein. - View Dependent Claims (2, 3, 4)
- and comprising a centrally bored first stopper adapted for insertion in the container opening and receiving the syringe access fitting in the bore thereof; and
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5. In a two-chamber syringe assembly for initially isolating a first liquid component to be provided in one chamber thereof from a second component to be provided in a second chamber thereof and thereafter mixing the two components;
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
a container providing a second chamber for the second component and having an opening at one end;
a first axially bored resilient stopper in the form of a sleeve, with one end thereof adapted for sealed engagement with the open end of the container and the bore thereof adapted for mounting the dispensing fitting of the cylinder therein in sealed engagement therewith at its other end; and
a second stopper adapted for mounting in the bore of the first stopper below the dispensing fitting in sealed engagement with the first stopper to seal off the piston cylinder chamber and included liquid component from the other component in the second chamber during storage and transport, the second stopper being ejectable from the bore of the first stopper after mounting therein into the second chamber upon actuation of the piston inwardly of the cylinder to communicate the two chambers for mixing the components in the second chamber, the improvement wherein the axial bore of the first stopper has an outward recessed portion of predetermined shape and the second stopper has an outward enlargement of complemental shape to that of the said recessed portion for sealed and releasable interengagement therewith.
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
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6. In a two-chamber syringe assembly for initially isolating a first liquid component to be provided in one chamber thereof from a second component to be provided in a second chamber thereof and thereafter mixing the two components;
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
a container providing a second chamber for the second component and having an opening at one end;
a first axially bored resilient stopper in the form of a sleeve, with one end thereof adapted for sealed engagement with the open end of the container and the bore thereof adapted for mounting the dispensing fitting of the cylinder therein in sealed engagement therewith at its other end; and
a second stopper adapted for mounting in the bore of the first stopper below the dispensing fitting in sealed engagement with the first stopper to seal off the piston cylinder chamber and included liquid component from the other component in the second chamber during storage and transport, the second stopper being ejectable from the bore of the first stopper after mounting therein into the second chamber upon actuation of the piston inwardly of the cylinder to communicate the two chambers for mixing the components in the second chamber, the improvement wherein the second stopper is provided with a depending collar having openings therethrough and a continuous annular lamella exteriorly therearound.
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
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7. In a two-chamber syringe assembly for initially isolating a first liquid component to be provided in one chamber thereof from a second component to be provided in a second chamber thereof and thereafter mixing the two components;
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
a container providing a second chamber for the second component and having an opening at one end;
a first axially bored resilient stopper in the form of a sleeve, with one end thereof adapted for sealed engagement with the open end of the container and the bore thereof adapted for mounting the dispensing fitting of the cylinder therein in sealed engagement therewith at its other end; and
a second stopper adapted for mounting in the bore of the first stopper below the dispensing fitting in sealed engagement with the first stopper to seal off the piston cylinder chamber and included liquid component from the other component in the second chamber during storage and transport, the second stopper being ejectable from the bore of the first stopper after mounting therein into the second chamber upon actuation of the piston inwardly of the cylinder to communicate the two chambers for mixing the components in the second chamber, the improvement wherein the end of the second stopper within the enlargement is recessed to receive the end of dispensing fitting of the syringe.
- comprising a piston and cylinder type syringe having an axially-bored dispensing fitting at one end of the cylinder, with the cylinder forming a chamber for the liquid component when the piston is in outward retracted position at the opposite end of the cylinder;
Specification